盆底肌训练结合盐酸奥昔布宁在缓解女性膀胱过度活动症中的效果  

Effect of pelvic floor muscle training combined with oxybutynin hydrochloride in relief of female patients with overactive bladder syndrome

作　　者：景硕[1] 

机构地区：[1]首都医科大学附属北京世纪坛医院泌尿外科,北京100038

出　　处：《实用临床医药杂志》2016年第10期128-130,134,共4页Journal of Clinical Medicine in Practice

摘　　要：目的探讨盆底肌训练在缓解女性膀胱过度活动症(OAB)患者症状中的效果。方法选取120例女性OAB患者中配合完成研究者110例,随机分为观察组50例(盆底肌训练加盐酸奥昔布宁治疗)和对照组60例(常规盐酸奥昔布宁治疗),比较2组患者干预前及干预14 d、30 d、90 d、6个月的膀胱过度活动症症状评分(OABSS),比较2组患者干预前及干预14 d、30 d、90 d的盆底肌肌力牛津分级,并比较2组患者干预前及干预90 d、6个月的King生活质量量表评分。结果治疗30 d、90 d后,观察组患者盆底肌力得分分别为(3.23±0.52)、(3.49±0.50)分,高于对照组的(3.03±0.54)、(2.97±0.62)分,差异有统计学意义(P<0.05);治疗后6个月随访时,观察组OABSS评分为(1.17±1.87)分,低于对照组的(2.56±2.03)分,差异有统计学意义(P<0.05);治疗90 d后,2组King生活质量量表中总体健康感受、行为受限、排尿问题严重性、运动受限、社交受限、症状严重程度得分比较,差异有统计学意义(P<0.05)。结论盆底肌训练结合盐酸奥昔布宁治疗能有效缓解女性OAB症状。Objective To explore the efficacy of pelvic floor muscle training（ PFMT） in the relief of female patients with overactive bladder syndrome（ OAB）. Methods A total of 110 female patients with OAB were randomly divided into two groups. The observation group（ n = 50） was given PFMT combined with oxybutynin hydrochloride,while the control group（ n = 60） was given oxybutynin hydrochloride. OAB symptom score（ OABSS） was compared between two group at the time points of before intervention and 14,30,90 days as well as 6 months after intervention. Modified Oxford scale（ MOS） was compared between two groups at the time points of before intervention and 14,30,90 days after intervention. King＇s health questionnaire（ KHQ） was compared between two groups at the time points of before intervention,90 days as well as 6 months after intervention. Results The30,90 days after treatment,The MOS scores were（ 3. 23 ± 0. 52） and（ 3. 49 ± 0. 50） in the observation group,which were significantly higher than（ 3. 03 ± 0. 54） and（ 2. 97 ± 0. 62） in the control group（ P〈0. 05）. The OABSS score was（ 1. 17 ± 1. 87） in the observation group after treatment of6 months,which was significantly lower than（ 2. 56 ± 2. 03） in the control group（ P〈0. 05）. There were significant differences in incontinence impact,role limitations,physical limitations,social limitations and symptom severity between two groups（ P〈0. 05）. Conclusion PFMT combined with oxybutynin hydrochloride can effectively alleviate the OAB in female patients.

关 键 词：盆底肌训练 盐酸奥昔布宁片 膀胱过度活动症 

分 类 号：R473.6[医药卫生—护理学]