孕妇HBsAg携带状态与产后首次喂养行为选择的关系  

The relationship between maternal HBsAg state and initiate feeding behavior in pregnant women

作　　者：郑东鸣 罗业飞 刘海燕[5] 熊海燕[1,2,3,4] 韩文晖[6] 汪艳[6] 胡安群[5] 王岳[1] 黄玥[1] 李意杰 郑英杰[1,2,3,4] 

机构地区：[1]复旦大学公共卫生学院卫生微生物学教研室,上海200032 [2]复旦大学公共卫生学院-教育部公共卫生重点实验室,上海200032 [3]国民健康社会风险预警协同创新中心,上海200032 [4]复旦大学卫生部卫生技术评估重点实验室,上海200032 [5]安徽省安庆市立医院检验科,安庆246003 [6]安徽省安庆市立医院妇产科,安庆246003

出　　处：《复旦学报（医学版）》2016年第3期328-332,共5页Fudan University Journal of Medical Sciences

基　　金：国家自然科学基金(81373065);上海市教育委员会科研创新重点项目(14ZZ015)~~

摘　　要：目的探讨孕妇乙肝感染对产后首次喂养行为的影响。方法采用前瞻性研究,招募2014年1月1日至2015年1月31日到安庆市立医院就诊的住院孕妇,通过调查问卷及医院住院孕妇电子病历信息系统收集孕妇的基本信息,收集血清进行乙肝表面抗原(HBV surface antigen,HBsAg)检测,产后1周时电话随访活产分娩孕妇,获取首次喂养行为信息,并通过单因素和多因素统计方法分析乙肝感染与首次喂养行为的关联。结果共纳入1 826名孕妇。安庆市孕妇人群产后首次喂养以纯母乳方式为主(77.7%,1418/1826);HBeAg(+)/HBsAg(+)、HBeAg(-)/HBsAg(+)及HBsAg(-)3组孕妇产后首次喂养选择纯母乳方式的比例分别为70.8%(17/24),75.8%(91/120)和77.9%(1310/1682),差异无统计学意义。结论安庆市孕妇人群分娩后首次喂养方式中,母乳喂养比例较高,未发现HBV的携带状态影响孕妇产后首次喂养行为的选择。Objective To investigate the effect of hepatitis B virus infection on initiate feeding behavior of pregnant women in Anqing city. Methods A prospective study was conducted among pregnant women who were recruited from Jan.1,2014 to Jan.31,2015 in Anqing City hospital.The base-line information was collected by using the questionnaire and the electronic medical record information system.Serum samples were also collected for HBV surface antigen（HBsAg）test.Pregnant women who had live fetus were selected to follow up by using telephone and information about initiate feeding behavior was obtained.The single variate and multivariate analysis were used to compare the initiate feeding behavior by the HBV status. Results A total of 1 826 pregnant women were enrolled.Breastfeeding was the main choice（77.7%,1 418/1 826）after delivery.The initiate breastfeeding rate of HBeAg（＋）/HBsAg（＋）,HBeAg（＋）/HBsAg（＋）and HBsAg（-）group was 70.8%（17/24）,75.8%（91/120）and 77.9%（1 310/1 682）,respectively.The difference among three groups was not statistically significant. Conclusions Our results suggested that the initiate breastfeeding rate is high among pregnant women in Anqing city,and maternal HBV state did not have an obvious correlation with the initiate feeding ways.

关 键 词：乙肝感染 母乳喂养 孕妇 

分 类 号：R512.6[医药卫生—内科学] R183[医药卫生—临床医学]