藤梨根化学成分的研究Ⅱ  

Study on chemical constituents of Actinidia Chinensis Planch.(Ⅱ)

作　　者：何国浓[1,2] 王邦才 王辉[2] 樊莉 胡秀敏 

机构地区：[1]宁波市中医院,宁波315010 [2]浙江中医药大学,杭州310053 [3]北京市石景山区食品药品安全监控中心,北京100043

出　　处：《中华中医药杂志》2016年第6期2353-2355,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：浙江省中医药科技计划(No.2013ZA115)~~

摘　　要：目的:研究藤梨根(Actinidia chinensis Planch.)的化学成分。方法:利用反复硅胶柱色谱法、Sephadex LH-20凝胶柱色谱法、中压柱层析及半制备高效液相色谱等方法分离纯化;通过NMR、MS等光谱数据鉴定化合物结构。结果:分离得到8个化合物,分别鉴定为熊果酸(Ⅰ)、胡萝卜苷(Ⅱ)、2α,3α,24-三羟基乌苏烷-12-烯-28酸(Ⅲ)、芒柄花素(Ⅳ)、7,4’-二羟基黄酮(Ⅴ)、(Z)-9,10,11-三羟基-12-十八碳烯酸(Ⅵ)、2α,3α,19α,24-四羟基乌苏烷-12-烯-28-酸(Ⅶ)、丁香醛(Ⅷ)。结论:化合物Ⅴ、Ⅵ、Ⅷ为首次从本植物中分离得到。Objective： To investigate the chemical constituents of the Kiwi root of Actinidia chinensis Planch.. Methods： The constituents were isolated by repeated silica gel chromatography, Sephadex LH-20 gel column chromatography, medium pressure column chromatography and semi-preparative high performance liquid chromatography and their structures were elucidated by chemical properties and spectral analysis. Results： Eight compounds were isolated and their structures were identified to be ursolic acid（Ⅰ）, daucosterol（Ⅱ）, 2α,3α,24-trihydroxyurs-12-en-28-oic acid（Ⅲ）, Formononetin（Ⅳ）, 7,4＇-dihydroxyflavone（Ⅴ）,（Z）-9,10,11-trihydroxy-12-octadecenoic acid（Ⅵ）, 2α,3α,19α,24-tetrahydroxyurs-12-en-28-oic acid（Ⅶ）, syringaldehyde（Ⅷ）. Conclusion： Compounds Ⅴ, Ⅵ, Ⅷ are obtained from this plant for the first time.

关 键 词：藤梨根 化学成分 分离鉴定 

分 类 号：R284.1[医药卫生—中药学]