血清睾酮/促黄体生成素、促卵泡激素及促黄体生成素水平检测在诊断睾丸生精作用中的价值  

Value of serum T/LH,FSH and LH levels in the diagnosis of testicular spermatogenesis

作　　者：邓智标 

机构地区：[1]广东省佛山市顺德区龙江医院,528318

出　　处：《国际检验医学杂志》2016年第11期1508-1509,1512,共3页International Journal of Laboratory Medicine

摘　　要：目的观察血清睾酮(T)/促黄体生成素(LH)、促卵泡激素(FSH)、LH水平检测在临床睾丸生精作用诊断中的临床价值。方法选择2014年1月至2015年6月到佛山市顺德区龙江医院进行原发性不育检查的60例患者进行研究,并且选择同期来佛山市顺德区龙江医院进行体检的健康男性60例作为健康对照组,对所有研究对象进行T、FSH、LH水平检测,比较健康对照组和不孕组患者FSH、T/LH、LH水平,以及少精组、极度少精组、特发性无精组患者FSH、T/LH、LH水平,以及中度、重度和不可逆性睾丸生精障碍患者FSH、T/LH、LH水平。结果与健康对照组比较,不育组患者FSH、LH明显升高,而T/LH明显降低,差异有统计学意义(P<0.05)。与少精组比较,重度生精障碍组与不可逆性生精障碍组患者FSH与LH明显升高,而T/LH明显降低。与极度少精组比较,特发性无精组患者FSH与LH明显升高,而T/LH明显降低。与中度生精障碍组比较,重度生精障碍组与不可逆性生精障碍组患者FSH与LH明显升高,而T/LH明显降低。与重度生精障碍组比较,不可逆性生精障碍组患者FSH与LH明显升高,而T/LH明显降低。上述各组数据差异均有统计学意义(P<0.05)。结论 FSH、T/LH、LH水平在睾丸生精作用检测中具有重要的临床价值。Objective To observe the clinical value of serum testosterone/luteinizing hormone（T/LH）,follicle-stimulating hormone（FSH）and luteinizinghormone（LH）levels in the diagnosis of testicular spermatogenesis.Methods 60 patients who were examined with primary infertility were randomly selected in January 2014 to June 2015 from Longjiang hospital and 60 healthy males were selected as control group.The levels of T/LH,FSH and LH were tested in the control group and infertile group as well as in oligozoospermia group,extreme oligozoospermia group and idiopathic azoospermia group,which were also detected in patients with moderate,severe and irreversible testicular spermatogenic impairment.Results Compared with the control group,the levels of FSH and LH were higher,while T/LH was lower in the infertile group,and the differences had statistical significance（P〈0.05）.In addition,the levels of FSH and LH in severe testicular spermatogenic group and irreversible testicular spermatogenic group were significantly higher than that of oligozoospermia group（P〈0.05）,while T/LH was significantly lower（P〈0.05）.And FSH and LH levels of in idiopathic azoospermia group were significantly higher than that of extreme oligozoospermia group（P〈0.05）,while T/LH was significantly lower than that of extreme oligozoospermia group（P〈0.05）.Compared with the moderate spermatogenic impairment group,levels of FSH and LH in severe testicular spermatogenic group and irreversible testicular spermatogenic group were significantly higher（P〈0.05）,while T/LH was significantly lower（P〈0.05）.Compared with severe spermatogenesis impairment group,levels of FSH and LH were significantly higher than that of irreversible testicular spermatogenic group（P〈0.05）,while T/LH was significantly lower（P〈0.05）.Conclusion The levels of FSH,T/LH and LH have important clinical value in the diagnosis of testicular spermatogenesis.

关 键 词：促卵泡激素 促黄体生成素 睾酮 睾丸生精作用 

分 类 号：R446.19[医药卫生—诊断学] R698.2[医药卫生—临床医学]