内耳发育畸形及相关基因研究进展  

The Inner Ear Malformations and Related Gene Research

作　　者：黄煌 林迳苍 郑鸣[2] 许相洋 

机构地区：[1]泉州医学高等专科学校组织胚胎学教研室,泉州362000 [2]福建医科大学人体解剖与组织胚胎学系,福州350000

出　　处：《四川解剖学杂志》2016年第1期34-37,共4页Sichuan Journal of Anatomy

基　　金：泉州市科技局课题(2015Z46)

摘　　要：先天性内耳畸形是导致神经性耳聋的原因之一,其发生与遗传、胚胎发育的不同阶段出现停滞、病毒感染、药物、窒息等因素相关。内耳发育畸形表型多样,致病基因通过不同途径参与内耳的发生和发育过程。本文对先天性内耳畸形的胚胎病理、临床分类及相关基因研究和临床运用进行综述。Congenital ear deformities is one of the cause of sensorineural deafness,its occurrence is related with genetic,different stages of embryonic development stalled,viral infections,drugs,asphyxia and other factors.The inner ear malformation has phenotypic diversity,of which genes participate in the occurrence and development of the inner ear through different ways.In this review,the current state-of-the-art of congenital ear malformation embryo pathology,clinical classification and related gene research and clinical application,is described.

关 键 词：内耳 畸形 基因 研究 

分 类 号：R764.7[医药卫生—耳鼻咽喉科]