腹腔镜与开腹肝囊肿开窗引流术对患者肝功能及免疫功能的影响  

Influence of laparoscopic and open hepatic cyst fenestration on liver function and immune function

作　　者：刘吉平 张国胜 高志伟 高冰 杨秀梅 

机构地区：[1]抚宁区人民医院,河北秦皇岛066300 [2]抚宁区妇幼保健院

出　　处：《腹腔镜外科杂志》2016年第5期333-336,共4页Journal of Laparoscopic Surgery

摘　　要：目的:分析腹腔镜与开腹肝囊肿开窗引流术对患者肝功能及免疫功能的影响。方法:分析2011年1月至2016年1月收治的56例肝囊肿患者的临床资料。其中34例行腹腔镜开窗引流术(腹腔镜组),22例行开腹手术(开腹组)。对比两组患者手术前后肝功能及免疫功能指标的变化。结果:术后第1天,两组患者肝功能指标中ALT、AST、TBIL均较术前升高;术后第3天逐渐下降,术后第7天恢复正常水平。腹腔镜组患者术后T细胞亚群轻度降低,术后第7天基本恢复至术前水平;开腹组T细胞亚群术后第1天、第3天均较术前明显降低(P<0.05),术后第7天仍未恢复至术前水平(P<0.05)。结论:腹腔镜肝囊肿开窗引流术可引起患者术后短时间肝功能异常,但对免疫功能无明显影响,与开腹手术相比具有优越性。Objective： The study was aimed to analyze influence of laparoscopic and open hepatic cyst fenestration on liver function and immune function. Methods： The clinical data of 56 patients with hepatic cyst from Jan. 2011 to Jan. 2016 were analyzed. 56 patients were divided into laparoscopic group（ n = 34） and open group（ n = 22）. Liver function and immune function of the patients in two groups were compared. Results： On the first postoperative day,the levels of alanine aminotransferase（ ALT）,aspartate aminotransferase（ AST）,total bilirubin（ TBIL） in two groups increased,then gradually declined on the third day postoperatively,and returned to normal levels on 7th postoperative day. Although T cell subsets of the laparoscopic group slightly decreased after the surgery,yet basically returned to preoperative levels on the 7th postoperative day; the open group markedly decreased on postoperative 1 d and 3 d（ P 〈0. 05）,after 7 d did not restore to normal（ P 〈 0. 05）. Conclusions： Laparoscopic hepatic cyst fenestration can lead to abnormal liver function within short time,but has no obvious effect on the immune function,has advantages compared with laparotomy.

关 键 词：肝囊肿 开窗术 腹腔镜检查 剖腹术 肝功能 免疫功能 

分 类 号：R657.3[医药卫生—外科学]