机构地区:[1]兰州大学第二医院泌尿外科,730030 [2]天水市第一人民医院泌尿外科 [3]河西学院附属张掖人民医院泌尿外科 [4]酒钢集团职工医院泌尿外科 [5]临夏回族自治州人民医院泌尿外科 [6]甘肃省医学科学研究院泌尿外科 [7]甘肃省武威肿瘤医院泌尿外科 [8]武威市人民医院泌尿外科 [9]酒泉市人民医院泌尿外科 [10]酒泉市人民医院新城区分院泌尿外科 [11]靖远煤业集团有限责任公司总医院泌尿外科 [12]武威市凉州区医院泌尿外科 [13]金川集团有限公司职工医院泌尿外科 [14]定西市人民医院泌尿外科 [15]定西市第二人民医院泌尿外科 [16]金昌市人民医院泌尿外科 [17]酒泉市玉门油田医院泌尿外科 [18]解放军第一医院泌尿外科 [19]金昌市第一人民医院泌尿外科 [20]兰州石油化工公司石化总医院泌尿外科 [21]甘肃省人民医院泌尿外科 [22]定西市临洮县人民医院泌尿外科 [23]陇南市徽县人民医院泌尿外科 [24]张掖市甘州区人民医院泌尿外科 [25]敦煌市人民医院泌尿外科 [26]白银市第一人民医院泌尿外科
出 处:《中华泌尿外科杂志》2016年第5期335-339,共5页Chinese Journal of Urology
基 金:兰州市科技项目(2010-1-85);兰州市城关区科技计划项目(2010-6-6)
摘 要:目的总结乙状结肠直肠膀胱术(MainzII)的10年经验及长期疗效。方法2004年10月至2014年12月甘肃省26家医院施行Mainz11术248例,男205例,女43例。年龄15—79岁,中位值61岁。248例中,膀胱恶性肿瘤239例,均经膀胱镜下活检确诊,包括尿路上皮癌230例,鳞癌6例,腺癌2例,平滑肌肉瘤1例;男性(200例)行根治性膀胱前列腺切除术,女性(39例)行全盆腔脏器切除术,均同时行双侧盆腔淋巴结清扫术。尿道鳞癌1例,行全盆腔脏器及尿道切除+双侧盆腔淋巴结清扫。泌尿系结核致膀胱挛缩、间质性膀胱炎、腺性膀胱炎、膀胱外翻、顽固性膀胱阴道瘘各1例,行单纯膀胱切除术。非可控尿流改道术后行MainzⅡ术改为可控性尿流改道者3例。回顾性分析248例患者的临床资料及随访情况,分析并发症发生情况、控尿情况、排尿次数及生活质量。结果本组248例手术的尿流改道时间为90-150min,中位值120min;估计失血量为400—2500ml,中位值800ml。围手术期病死率2.8%(7/248)。早期(≤30d)并发症发生率26.6%(66/248),包括肠瘘6例(2.4%),肺部感染5例(2.O%),肠梗阻、肾盂肾炎各4例(1.6%),深静脉血栓、盆腔感染各2例(0.8%),切口裂开10例(4.0%),切口感染30例(12.1%),失血性休克、心肌梗死、直肠阴道瘘各1例(0.4%)。围手术期存活者241例中,37例(15.4%)失访,85例死亡(41.7%,85/204),剩余119例随访7—126个月,中位值46个月。204例的远期(〉30d)并发症发生率29.4%(60/204),包括输尿管肠吻合口狭窄20例[9.8%,吻合单位狭窄率6.0%(24/400)],复发性肾盂肾炎12例(5.9%),延迟性肠梗阻11例(5.4%),有症状性代谢性酸中毒11例(5.4%),切口疝5例(2.5%),盆腔感染1例(0.5%)。接受随访的1Objective To report 10 years experience in modified ureterosigmoidostomy (Mainz Pouch Ⅱ ) urinary diversion and evaluate its long-term outcome. Methods From October 2004 to December 2014, 248 patients , including 205 men and 43 women, had underwent Mainz Pouch Ⅱ urinary diversion at 26 institutions in Gansu Province, China. The median age at surgery was 61 years, ranged from 15 to 79 years, Among those patients, 239 patinets were diagnosed as bladder invasive urothelial carcinoma, including umthelial carcinoma in 230, squamous cell carcinoma in 6, adenocarcinoma in 2 and leiomyosarcoma in 1. 200 male patients underwent the radical vesico-prostsectomy. 39 female patients underwent the exenteration of total pelvis with bilateral pelvic lymadenectomy. For one paitent with urethral squamous cell carcinoma, exenteration of total pelvis, urethra resection and bilateral pelvic lymadenectomy were performed at the same time. Simple eystectomy were performed in 5 patients, including bladder retraction as a consequence of urinary tuberculosis, exstrophy bladder, interstitial cystitis, glandular cystitis and refractory vesicovaginal fistula. Bricker ileal conduit urinary diversion was transformed to Mainz Pouch Ⅱ in three patients. Clinical data and early complications were retrospective analysis. Data on long-term complications, continent status, urinary frequency and patient's quality of life were investigated by follow- up. Results The median operative time for urinary diversion is 120 minutes (ranging from 90 to 150 minutes). The median estimated blood loss was 800 ml ( ranging from 400 to 2 500 ml). Seven patients (7/ 248, 2. 8% ) died in the perioperative period. Early complications were noticed in 66 patients (66/248, 26. 6% ), such as intestinal fistula(6/248, 2.4% ), pulmonary infection(5/248, 2. 0% ), ileal obstruction (4/248, 1.6% ), pyelonephritis ( 4/248, 1.6% ), deep venous thrombosis ( 2/248, 0. 8% ), pelvic infection(2/248, 0. 8% ), wound dehiscence ( 10/2
关 键 词:输尿管乙状结肠吻合术 尿流改道 MainzⅡ膀胱 手术并发症 随访
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