早产儿下肢静脉血栓3例报告  

Deep venous thrombosis in preterm infants: 3 cases report

作　　者：胡琦[1] 范文婷[1] 邓睿[2] 廖伟[1] 

机构地区：[1]第三军医大学附属西南医院儿科,重庆400038 [2]重庆市妇幼保健院新生儿科,重庆400013

出　　处：《临床儿科杂志》2016年第6期453-456,共4页Journal of Clinical Pediatrics

摘　　要：目的 提高对早产儿静脉血栓诊断及治疗的认识.方法 回顾性分析3 例早产儿下肢静脉血栓的临床特征、治疗经过及预后,并结合文献进行分析.结果 3例早产儿的胎龄29 - 36 周,出现血栓时间为出生1 - 57 d.1 例予外周静脉穿刺植入中心静脉导管（PICC）,3 例均有感染征象及创伤.予溶栓及抗凝治疗1 例,大剂量溶栓治疗1 例,此2 例均治疗成功且无出血并发症;另1 例患儿放弃治疗后病情恶化.结论 危重症早产儿是血栓症的高危人群.感染、置管、易栓体质及母亲高危因素均是血栓发生的高危因素.早发现、早诊断并采取合理有效的个体化治疗可改善预后.Objective To enhance the awareness of diagnose and treatment of venous thrombus in premature infants. MethodsThe clinical features, treatment and prognosis of lower limb vein thrombus in three case of premature infants were retrospectively analyzed.ResultsThree premature infants of gestational age 29-36 weeks were found thrombosis in 1-57 days after birth. One case received peripherally inserted central cathete (PICC). All of three cases had infection signs and trauma. One case received thrombolytic and anticoagulant therapy, one case received high dose thrombolytic therapy, and both of them were treated successfully without bleeding complication. However, another case was deteriorated after giving up treatment.ConclusionsCritically ill premature infants are at high risk of thrombosis. Infection, indwelling tube, thrombophilia constitution, and maternal risk factors were the high risk factors of thrombosis. Early detection, early diagnosis, and effective individualized treatment can improve the prognosis.

关 键 词：深静脉血栓 治疗 早产儿 

分 类 号：R722.6[医药卫生—儿科]