基于有限元模型的圆窗激振与正常感声下耳蜗微观动态特性  

Study on microscopic dynamic behaviors of cochlea between round window stimulation and normal acoustic stimulation based on the finite element model

作　　者：韩帅[1] 刘后广[1] 杨建华[1] 刘晓乐[1] 徐丹[1] 王梦丽[1] 

机构地区：[1]中国矿业大学机电工程学院,江苏徐州221116

出　　处：《中国科技论文》2016年第4期444-448,共5页China Sciencepaper

基　　金：高等学校博士学科点专项科研基金资助项目(20130095120010);国家自然科学基金资助项目(51305442);江苏省自然科学基金资助项目(BK20130194)

摘　　要：为了确定传统基于基底膜位移的评价指标用于圆窗激振式人工中耳是否准确,基于沙鼠耳蜗微观扫描电镜图,建立了耳蜗Corti器三维有限元力学模型。通过与文献中的实验结果对比,对模型进行验证,最后,基于该模型,对比分析圆窗激振和正常感声下基底膜、内毛细胞纤毛、外毛细胞纤毛的动态特性。结果表明:在评价圆窗激振式人工中耳的听力补偿性能时,将基底膜的运动位移作为评价指标将高估其实际的听力补偿效果。In order to determine whether it is precise to use basilar membrane displacement as an evaluating standard for the RWstimulation type middle ear implant,a three dimensional finite element model of the organ of Corti was established based on the scanning electron micrograph of a gerbil cochlea.Then,the validity of this model was confirmed by comparing with the experimental results in the reference.Finally,a comparative study concerning the RW-simulation and normal acoustic stimulation was conducted,and the corresponding displacements of the basilar membrane,inner hair cell stereocilia and outer hair cell stereocilia were derived.The results show that using the displacement of basilar membrane as the evaluating standard overestimates its actual hearing compensation effect for the RW-simulation type middle ear implant.

关 键 词：人工中耳 耳蜗 圆窗 CORTI器 剪切运动 

分 类 号：R764[医药卫生—耳鼻咽喉科]