功能化氧化石墨烯载药控释性能的研究现状  

A Review on Functional Graphene Oxide Property of Drug Delivery

作　　者：钱文昊[1,2] 苏俭生[1] 

机构地区：[1]同济大学口腔医学院口腔修复教研室,上海牙组织修复与再生工程技术研究中心,上海200072 [2]上海市徐汇区牙病防治所,上海200032

出　　处：《上海第二工业大学学报》2016年第2期88-93,共6页Journal of Shanghai Polytechnic University

基　　金：国家自然科学基金(No.81371949,No.81572114);上海市生物医药科技重点项目(No.13411951200)资助

摘　　要：氧化石墨烯载药应用于医学的预防和治疗领域是目前研究的热点。综述了近年来氧化石墨烯及其衍生物作为药物载体在控释性能及其生物安全性方面的最新研究。证实了氧化石墨烯兼具被动靶向及大量可接入活性基团的优点,是发展靶向纳米药物传输的理想载体。The prevention and treatment of graphene oxide drug delivery used in medicine is a hot topic at present. This paper reviewsthe graphene oxide and its derivatives as drug carriers in controlled release properties and biological safety of the latest research. It isconfirmed that the graphene oxide both advantages of passive targeting and a large number of active groups, which is an ideal carrier tothe development of nano drug delivery target.

关 键 词：氧化石墨烯 载药 控释 

分 类 号：TQ127.11[化学工程—无机化工] R943[医药卫生—药剂学]