卫星细胞对运动性肌损伤修复机制的研究进展  

The Research Progresses on Skeletal Muscle Satellite Cells and its Repair Mechanism of Injured Muscle

作　　者：杨金娟[1] 刘英杰[1] 林家仕[1] 关伟军[2] 白春雨[2] 金兵站 

机构地区：[1]集美大学体育学院,福建厦门361021 [2]中国农业科学院北京畜牧兽医研究所种质资源保存实验室,北京100193

出　　处：《体育科学研究》2016年第3期61-65,共5页Sports Science Research

基　　金：国家自然科学基金项目(31472099)

摘　　要：为了探寻肌肉卫星细胞在运动性肌肉损伤修复中的作用,对肌肉卫星细胞异质性、不对称分裂及卫星细胞信号通路等知识进行了综述。讨论了肌肉卫星细胞自我更新机制及功能调控过程,探讨了体育运动对卫星细胞增殖、分化等的影响。在此基础上,对以干细胞技术为基础的卫星细胞移植疗法促进运动性肌肉损伤修复进行展望。In order to explore the role of muscle satellite cells in muscle injuries in sports,this review mainly explained the knowledge of heterogeneity,asymmetric division and signaling pathway of satellite cells,discussed its self- renewal mechanism and regulation process,the effects of sports exercise on growth,proliferation and differentiation of satellite cells were explored.On this basis,satellite cell transplantation therapy based on stem cell technology was prospected to enhance the repairmen of muscle injuries.

关 键 词：肌肉卫星细胞 肌肉损伤 修复机制 体育运动 

分 类 号：G804.2[文化科学—运动人体科学]