中西药联合治疗早期糖尿病肾病疗效及对尿蛋白的影响  

Effects of integrated Chinese and western medicine on early diabetic nephropathy and urine protein

作　　者：王峥[1] 

机构地区：[1]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医临床研究》2016年第6期65-66,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的:研究探讨中西药联合治疗早期糖尿病肾病疗效及对尿蛋白的影响。方法:两组患者接受不同治疗方法。将两组患者血清胱抑素C、尿微量白蛋白浓度及尿蛋白含量进行对比。结果:观察组患者治疗后血清胱抑素C水平下降(0.30±0.05)mg/L,对照组下降(0.12±0.02)mg/L,经检验具有统计学意义(P<0.01)。观察组患者治疗后尿微量白蛋白浓度下降(48.26±5.02)mg/L,对照组下降(24.25±3.15)mg/L,经检验具统计学意义(P<0.01)。观察组患者尿蛋白含量为(0.29±0.05)g/L,对照组患者尿蛋白含量为(0.75±0.12)g/L,经检验具统计学意义(P<0.05)。结论:中西药联合治疗能发挥各种药物的优势,有效延缓患者肾功能恶化,降低尿中蛋白含量。Objective: To study the effects of integrated Chinese and western medicine on early diabetic nephropathy and urine protein. Methods:Two groups of patients with different treatment methods were taken for study. Serum cystatin C, microalbuminuria concentration and Urinary protein content were compared between the groups after the treatment. Results: The levels of cystatin C after the treatment was respectively(0.30±0.05)mg/L and(0.12±0.02)mg/L in treatment group patients and control group patients.withstatistical significance(P<0.01). The microalbuminuria concentrationof the treatment group patients and control grouprespectively decreased to(48.26±5.02)mg/L and(24.2±3.15)mg/Lwith.statistical significance(P<0.01). The urinary protein contentwas(0.75±0.12) g/L in the treatment group and(0.75±0.12) g/L in the control group after treatment. Statistical significance(P<0.05) was tested. Conclusion: The advantages of integrated Chinese and western medicinein the treatment ofearly diabetic nephropathy can effectively delay the deterioration of renal function in patients and reduce urinary protein content.

关 键 词：中西药联合 糖尿病肾病 尿蛋白 

分 类 号：R255.4[医药卫生—中医内科学]