胎儿肺动脉血流指数与胎儿肺成熟度相关性研究  

Corrlation between fetal pulmonary blood flow index and fetal lung maturity

作　　者：刘翠玲[1] 卢慧彬[1] 邓惠玲[1] 

机构地区：[1]中山市陈星海医院超声科,528415

出　　处：《国际医药卫生导报》2016年第12期1679-1681,1686,共4页International Medicine and Health Guidance News

基　　金：广东省中山市科技局立项项目（20132A043）

摘　　要：目的探讨肺动脉阻力与搏动指数（resistanceindex，pulsatilityindex，RIPA）在胎儿肺成熟度ffetallungmaturity，FLM）预测中的临床价值。方法选择妊娠37—40周的胎儿305例，根据羊水泡沫试验和Apgar评分分为异常组15例和正常对照组290例，应用彩色多普勒超声检测每例胎儿的RIPA。结果正常胎儿RIPA随着孕龄的增加而逐渐减小，两者具有高度相关性（r=-0．98，P〈0．05）。正常对照组胎儿RIPA为（0．82±0．02），显著低于异常组的（0．86±0．01）（P〈0．05）。结论胎儿RIPA在整个妊娠期中表现出规律性变化，胎儿RIPA的变化与胎肺成熟度密切相关，能够作为临床评估胎儿胎肺发育的有效方法。Objective To investigate the clinical value of pulmonary arterial resistance and pulsatility index （RIPA） in the prediction of fetal lung maturity （FLM）. Methods 305 fetuses of 37 - 40 weeks pregnancy were selected. According to the foam test of amniotic fluid and Apgar score they were divided into an abnormal group （15 cases） and a normal control group （290 cases）. Color Doppler ultrasound was used to detect fetal RIPA in each case. Results The RIPA of the normal fetuses decreased with the increase of gestational age; these two were highly correlated （r=-0.98, P 〈 0.05）. The RIPA of the normal fetuses was （0.82 ± 0.02） and that of the abnormal group （0.86 ± 0.01） （P 〈 0.05）. Conclusions Fetal RIPA in the pregnancy regularly changes. Fetal RIPA change closely relates with fetal lung maturity. Fetal RIPA can effectively and clinically assess fetal lung development.

关 键 词：肺动脉 肺成熟 胎儿 彩色多普勒超声 

分 类 号：R714.5[医药卫生—妇产科学] R445.1[医药卫生—临床医学]