丹参注射液穴位注射改善糖耐量异常的临床对照研究  

Injectio salviac mihiorrhizae composita point injection improved IGT:a randomized controlled trial

作　　者：舒晴[1,2] 梁凤霞[1,2] 陈瑞[3] 陈丽[1,2] 何文娟[1,2] 

机构地区：[1]湖北中医药大学针灸骨伤学院,武汉430061 [2]针灸治未病湖北省协同创新中心,武汉430061 [3]华中科技大学同济医学院附属协和医院中西医结合科,武汉430022

出　　处：《中国中西医结合消化杂志》2016年第5期333-338,共6页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：国家自然科学基金面上项目(No:81473787)

摘　　要：[目的]观察丹参注射液穴位注射干预糖耐量异常(IGT)的临床疗效。[方法]将64例IGT患者按随机数字表分为穴位注射组(32例)和对照组(32例)。穴位注射组采用丹参注射液穴位注射并配合合理饮食运动干预,对照组用单纯饮食运动干预。检测IGT人群干预前后的空腹血糖、餐后2h血糖、空腹胰岛素及餐后2h胰岛素,分别计算出2组人群的HOMA-IR值。将2组空腹血糖、餐后2h血糖、HOMA-IR值、及中医症状积分进行统计学分析。[结果]穴位注射组和对照组中医症状积分,餐后2h血糖,穴位注射组HOMA-IR值与对照组比较有显著性差异(P<0.01),2组IGT人群干预前后空腹血糖改善差异无统计学意义(P>0.05)。[结论]丹参注射液穴位注射对IGT人群具有良好的干预作用。[Objective]To investigate the clinical efficacy of injectio salviac mihiorrhizae composita point injection on impaired glucose tolerance（IGT）patients.[Methods]Sixty-four IGT patients were randomly divided into a point injection group（32cases）and a control group（32cases）.The treatment group was treated by injectio salviac mihiorrhizae composita point injection on the base of diet and exercise intervention.The control group was simply treated by diet and exercise intervention.The fasting blood glucose（FBS）,postprandial two hour blood glucose（P2hBS）,fasting insulin（FINS）and postprandial two hours insulin（P2hINS）were measured,and HOMA-IR values of two groups were respectively calculated before and after the intervention.An statistic evaluation was made by FBS,P2 hBS,FINS,P2 hINS,HOMA-IR values and TCM symptom score.[Results]The TCM symptom score,P2 hBS and HOMA-IR values was significantly different in the point injection and control groups（P〈0.01）.There was no significant difference between the two groups in the FBS（P〉0.05）.[Conclusion]Injectio salviac mihiorrhizae composita point injection has a good intervention effect on IGT patients.

关 键 词：丹参注射液 穴位注射 糖耐量异常 胰岛素抵抗 

分 类 号：R58[医药卫生—内分泌]