固本安神合剂的制备工艺研究  

Study on Preparation of Gubenanshen Mixture

作　　者：李文兵[1] 张诚光[1] 王洛临 李智勇 范宋玲[1] 

机构地区：[1]广东省第二中医院,广东广州510095 [2]广东省中医药工程技术研究院,广东广州510095

出　　处：《今日药学》2016年第5期335-337,320,共4页Pharmacy Today

摘　　要：目的确定固本安神合剂的制备工艺。方法以绿原酸含量和固形物含量为指标,采用正交实验法优选提取工艺,并对成型工艺进行研究。结果采用水提取工艺,最佳工艺为提取2次,每次加8倍水,每次提取1 h。滤液合并,减压浓缩至约900 mL,滤过,加蔗糖150 g等配制即得。结论优选的提取工艺和制备工艺稳定可行,可满足生产的需求。OBJECTIVE To determine the preparation of Gubenanshen mixture. METHODS The content of chlorogenic acid and solids were used as indicators,orthogonal experimental method was used to optimize the extraction process,and the molding process was studied. RESULTS The water extraction technology was used,the optimum extraction process was extracted twice,each with 8 times of water,1 h each time. The combined filtrate was concentrated under reduced pressure to about 900 mL,filtration,add 150 g sugar etc.,and get the preparation. CONCLUSION The preferred extraction process and the preparation process are stable,and it can meet the production needs.

关 键 词：固本安神合剂 提取工艺 制备工艺 

分 类 号：R283[医药卫生—中药学]