应用静息态功能磁共振技术研究针刺太溪穴对老年人脑网络的影响  

Brain network research on acupuncture at Taixi in the elderly adults based on resting-state functional magnetic resonance imaging

作　　者：王单[1] 吕敦召 帅记焱[2] 温秀云[1] 谭婷婷[1] 黄居科[1] 谢红亮[1] 殷亮[1] 梁久平[1] 陈尚杰[1] 

机构地区：[1]南方医科大学附属深圳宝安医院,广东深圳518101 [2]南昌大学附属九江医院

出　　处：《中国老年学杂志》2016年第12期2986-2988,共3页Chinese Journal of Gerontology

基　　金：国家自然科学基金面上项目(No.81173354);广东省科技计划项目(No.2013B021800099);深圳市科技创新委员会项目(No.JCYJ20150402152005642);深圳市宝安科技计划项目(No.2013039)

摘　　要：目的采用无创的静息态功能磁共振技术,探讨真针刺和浅刺太溪穴对老年人脑网络的影响。方法选取老年人12名,在不同时间段分别真针刺和浅刺患者右侧太溪穴,针刺后用视觉模拟评分来评估受试者的针感强度。在针刺的前后分别采集功能性磁共振影像资料,分析脑网络连接变化。结果真针刺组较浅刺组酸、麻、胀、温热的感觉强度更大。真针刺组与浅刺组相比,海马与尾状核之间连接强度最大,其次为眼眶部前额叶皮质与海马之间的连接,以及大脑岛叶与壳核,颞中回与眼眶部前额叶皮质的网络连接较强。结论真针刺较浅刺组具有更强的针感,并且使大脑的网络连接的相互作用增强。Objective To explore the real acupuncture and shallow acupuncture effect on brain network in the elderly, which pro- vides scientific basis for the effect of acupuncture at Taixi on anti-aging. Methods Twelve elderly adults were enrolled and respectively re- ceived real acupuncture and shallow acupuncture at Taixi at different time periods. Visual analogue scales （VAS） was used to evaluate the acupuncture sensation after acupuncture. FMRI data were collected before and after acupuncture, and the brain network connectivity changes were analyzed in this study. Results The acupuncture sensation such as soreness,numbness,fullness and warmth were found to be stronger for real acupuncture than shallow acupuncture. Compared the effective connectivity of network between real acupuncture and shallow acupunc- ture at Taixi in the elderly adults, the connectivity strength between the hippocampus and caudate nucleus is the greatest, followed by the con- nectivities between orbital prefrontal cortex and hippocampus, insula and putamen , the middle temporal gyrus and orbital prefrontal cortex. Conclusions Compared with shallow acupuncture, real acupuncture could induce stronger acupuncture sensation and increase the interaction of brain network connectivity.

关 键 词：功能性磁共振成像 针刺 太溪穴 

分 类 号：R445.2[医药卫生—影像医学与核医学] R322.81[医药卫生—诊断学]