T_2*-PWI联合DCE-MRI及DWI对乳腺病变的诊断价值  

The diagnostic value of T_2*-PWI combined with DCE-MRI and DWI for diagnosis of breast lesions

作　　者：孙冬[1] 郭大静[1] 赵建农[1] 

机构地区：[1]重庆医科大学附属二院放射科,重庆400010

出　　处：《放射学实践》2016年第6期501-505,共5页Radiologic Practice

摘　　要：目的:探讨T2*加权灌注成像联合动态增强磁共振成像(DCE-MRI)、磁共振弥散加权成像(DWI)对乳腺良恶性病变鉴别诊断的价值。方法:3.0T MRI系统对64例乳腺病变患者依次行常规的MRI平扫、T2*-PWI、DCE-MRI和DWI检查。通过统计学分别评价DCE-MRI,DCE-MRI及DWI,T2*-PWI及DCE-MRI,T2*-PWI、DCE-MRI及DWI 4种方法对乳腺良恶性病变的诊断价值。结果:DWI、T2*PWI及DCE-MRI组合模式具有较高的诊断价值,其敏感度、特异度、准确度、ROC曲线下面积(AUC)分别为97.8%、88%、94.2%、0.929。结论:T2*-PWI有助于乳腺良恶性病的鉴别诊断,具有较高的特异性。T2*-PWI联合DCE-MRI、DWI该种组合模式可明显提高MRI对乳腺良恶性病变诊断的价值,具有较高的准确性、特异性。Objective：To compare the diagnostic value of dynamic contrast-enhanced（DCE）magnetic resonance imaging（MRI）as a single parameter to multiparametric（MP）MRI with 2（DCE MRI and diffusion weighted imaging[DWI]）and 3（DCE MRI,DWI,and T2＊-perfusion weighted imaging [T2＊-PWI]）parameters in the diagnosis of breast tumors.Methods：Routine plain MRI,DCE MRI,DWI and T2＊-PWI were performed on breasts in sixty-four female patients with breast tumors before operation.The diagnostic value of DCE MRI as a single parameter was compared to MP MRI with 2（DCE MRI and DWI）and 3（DCE-MRI,DWI,and T2＊-PWI）parameters in the diagnosis of breast tumors.Results：The diagnostic value of MP MRI with 3（DCE-MRI,DWI,and T2＊-PWI）parameters in breast tumors was highest.The sensitivity,specificity,accuracy and area under roc curve（AUC）was 97.8%,88%,94.2% and 0.929,respectively.Conclusion：T2＊-PWI yielded higher specificity in the differential diagnosis between benign and malignant breast disease.In this study,MP MRI with 3（DCE-MRI,DWI,and T2＊-PWI）parameters can significantly improve the diagnostic value to differentiate benign from malignant breast lesions and have a higher accuracy and specificity.

关 键 词：乳腺病变 扩散磁共振成像 诊断 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]