我院永久性心脏起搏器植入术围术期预防使用抗菌药物专项整治效果分析  

Effects Analysis of Special Rectification of Antibiotics for Prophylactic Use in Perioperative Period of Permanent Cardiac Pacemaker Implantation in Our Hospital

作　　者：张晓娟[1] 陈纪言[2] 陈泗林[2] 杨敏[1] 

机构地区：[1]广东省人民医院/广东省医学科学院药学部,广州510080 [2]广东省人民医院/广东省医学科学院心血管内科,广州510080

出　　处：《中国药房》2016年第17期2333-2335,共3页China Pharmacy

摘　　要：目的:为永久性心脏起搏器植入术围术期合理预防使用抗菌药物提供参考。方法:随机抽取我院抗菌药物专项整治前(2010年)、整治中(2012年)和整治后(2014年)永久性心脏起搏器植入术病例各200例,分别纳入对照组、干预1组和干预2组,对各组患者预防使用抗菌药物的情况进行调查分析。结果:对照组、干预1组和干预2组患者预防使用抗菌药物品种选择合理率分别为7.25%、31.00%和91.96%;预防使用抗菌药物时机合理率分别为0、100%和100%;平均预防用药天数由整治前的(3.6±1.2)d缩短至整治中的(1.1±0.5)d和整治后的(1.0±0.2)d。各组患者术后感染的发生率比较,差异无统计学意义(P>0.05)。与对照组相比,2个干预组患者的平均药品费用、抗菌药物费用和药占比均明显下降,差异有统计学意义(P<0.05)。结论:我院抗菌药物专项整治活动效果明显,有助于抗菌药物的合理使用。OBJECTIVE：To provide reference for rational prophylactic application of antibiotics in perioperative period of permanent cardiac pacemaker implantation. METHODS：600 cases performed permanent cardiac pacemaker implantation in 2010（before rectification）,2012（during rectification）and 2014（after rectification）were randomly sampled from our hospital,and divided into control group,intervention group one and intervention group two. The prophylactic application of antibiotics was investigated and analyzed in 3 groups. RESULTS：For control group,intervention group one and intervention group two,the rates of rational type selection of antibiotics for prophylactic use were 7.25%,31.00% and 91.96%,respectively. The rates of rational medication timing of antibiotics for prophylactic use were 0,100% and 100%;average duration of prophylactic use decreased from（3.6 ±1.2）d before intervention to（1.1±0.5）d and（1.0±0.2）d. There was no statistical significance in the incidence of postoperative infection（P〉0.05）. Compared with control group,average drug cost,antibiotics cost and drug ratio decreased significantly in intervention group,with statistical significane（P〈0.05）. CONCLUSIONS：Antibiotics special rectification is effective and improve the rational application of antibiotics in our hospital.

关 键 词：永久性心脏起搏器植入术 围术期 抗菌药物 预防使用 专项整治 

分 类 号：R978.1[医药卫生—药品] R969.3[医药卫生—药学]