妊娠期易栓症患者血小板参数、凝血相关指标改变及临床意义  

Changes and clinical significance of platelet and coagulation parameters in pregnant women with thrombophilia

作　　者：李末娟 熊丹[2] 高红梅 林还珠 

机构地区：[1]广东省湛江市第二人民医院妇产科,广东湛江524000 [2]广东医学院附属医院血液内科,广东湛江524001

出　　处：《广东医学院学报》2016年第1期55-57,共3页Journal of Guangdong Medical College

摘　　要：目的观察妊娠期易栓症患者血小板参数、凝血相关指标的改变及临床意义。方法比较51例妊娠期易栓症患者和40例正常晚期孕妇的血小板参数及凝血相关指标。结果易栓症组凝血酶原时间、凝血酶原时间比值、抗凝血酶III均低于正常晚孕组(P<0.05),而部分凝血酶时间、血小板平均体积和分布宽度均高于正常晚孕组(P<0.05)。结论监测孕产妇血小板和凝血相关指标可预防易栓症和改善妊娠结局。Objective To observe the changes and clinical significance of platelet and coagulation parameters in pregnant women with thrombophilia. Methods The platelet and coagulation parameters were compared between 51 pregnant women with thrombophilia and 40 normal late pregnant women. Results Compared with normal late pregnant women, prothrombin time and its ratio, antithrombin III level were decreased（P〈0.05）, while partial thromboplastin time and mean platelet volume and distribution width were increased in thrombophilia group（P〈0.05）. Conclusion The monitoring of platelet and coagulation indexes in pregnant women can prevent the thrombophilia and improve the pregnancy outcome.

关 键 词：易栓症 凝血指标 血小板 

分 类 号：R714.25[医药卫生—妇产科学]