剪切波弹性成像技术评估乳腺病变的方法学探讨  

Optimal Methodology of Shear Wave Elastography in Assessing Breast Lesions

作　　者：韩竞[1] 李安华[1] 韩峰[1] 林庆光[1] 庄淑莲 林僖[1] 

机构地区：[1]中山大学肿瘤防治中心超声科,广州市510060

出　　处：《中国超声医学杂志》2016年第6期503-506,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探索剪切波弹性成像(SWE)技术评估乳腺病变的优化方法学。方法对48例女性患者共51个病灶行SWE测定。(1)成像模式(标准模式,Sta;穿透力模式,Pen);(2)耦合剂用量(适量及足量),在两种情况下观察病灶的成像特征及各弹性参数。结果 (1)51个乳腺病灶在Sta模式下,39个出现彩色充盈不全;在Pen模式、足量耦合剂条件下仅3个病灶出现彩色充盈不全。(2)Pen模式、足量耦合剂条件下,20个病灶弹性图像伪像减少;适量较足量耦合剂扫查条件下所得弹性参数Emax、Emean、Esd(kPa)(P<0.05)偏大,两种条件下,弹性参数(Emax、Emean、Esd)鉴别良恶性病变ROC曲线下面积及截点不同。结论剪切波弹性成像评估乳腺病灶的方法学直接影响到定性、定量分析的结果,因此选择正确、规范化的操作方法至关重要。Objective To explore the optimal methodology of shear wave elastography in assessing breast lesions.Methods 51 breast nodules in 48 women were examined by shear wave elastography.Evaluating the elastographic features and parameters of the nodules in the following situations.（1）Standard or penetration scanning modes（2）moderate or enough coupling jelly.Results（1）39 of 51 nodules displayed filling defect color pattern at standard mode,however only 3 of 51 nodules at penetration mode when using enough coupling jelly.（2）Image artifacts were reduced in 20 nodules at penetration mode when using enough coupling jelly.The elastographic parameters gotten were higher by using moderate than enough coupling jelly（P0.05）.Under the above two conditions,the parameters（Emax、Emean and Esd）were both different from malignant nodules to benign ones,but with the different Az values（area under ROC curve）and cutoff values.Conclusions The optimal methodology we advanced is essential to the shear wave elastography in assessing breast nodules qualitatively and quantitatively,the correct and strict procedure,which are essential for getting precise result.

关 键 词：剪切波弹性成像技术 乳腺病变 定性评估 定量评估 方法学 

分 类 号：R445.1[医药卫生—影像医学与核医学]