不同真空负压下甲状腺结节细针抽吸活检的比较  

Comparison of Fine Needle Aspiration Biopsy with Different Vacuum Pressure for Diagnosis of Thyroid Nodule

作　　者：沈浩霖[1] 吕国荣 杨舒萍[1] 蔡晓菡[1] 廖丽萍[1] 郑春暖 王丽菊[3] 

机构地区：[1]福建医科大学附属漳州市医院超声医学科,福建省漳州市363000 [2]泉州市医学高等专科学校 [3]福建医科大学附属漳州市医院病理科,福建省漳州市363000

出　　处：《中国超声医学杂志》2016年第6期551-553,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的评价不同真空负压细针抽吸活检(FNAB)诊断甲状腺良恶性结节的价值。方法 80例可疑恶性甲状腺结节患者行超声引导25GFNAB,比较5、10ml及15ml真空压力负荷FNAB的诊断效能。结果 10 ml真空压力负荷FNAB标本合格率为93.7%,高于5 ml及15 ml真空压力负荷FNAB(分别为85.7%和84.9%);10ml真空压力负荷FNAB诊断甲状腺恶性结节的灵敏度、特异度和符合率(分别为87.0%、93.6%和92.1%)明显高于5ml及15 ml真空压力负荷FNAB的灵敏度、特异度和符合率(分别为60.9%、80.8%和76.2%,56.5%、78.2%和73.3%)(P<0.05)。5、10ml及15ml真空压力负荷FNAB的ROC(receiver operating characteristic)曲线下面积(AUC)分别为0.756、0.899、0.737。结论 10ml真空压力负荷FNAB对甲状腺结节具有较高的诊断效能。Objective To evaluate the accuracy of fine-needle aspiration biopsy（FNAB）with different vacuum pressure for the diagnosis of thyroid nodules.Methods 80 cases of patients with thyroid nodules underwent FNAB.The diagnostic accuracy and complication rate of FNBA with 5 ml,10 ml and 15 ml vacuum pressure in the diagnosis of thyroid nodules were compared.Results The satisfactory samples rate of FNAB with 10 ml vacuum pressure was 93.7%,higher than that of 5 ml and 15 ml vacuum pressure（85.7% and 84.9%,respectively）.The sensitivity,accuracy and specificity of FNAB with 10 ml vacuum pressure（87.0%,93.6% and 92.1%）were all significantly higher than those of FNAB with 5 ml vacuum pressure（60.9%,80.8% and 76.2%）and those of with 15 ml vacuum pressure（56.5%,78.2% and 73.3%）,and the differences were statistically significant（P 0.05）.The area under the curve（AUC）of receiver operating characteristic（ROC）of FNAB with 5 ml,10 ml and 15 ml vacuum pressure were 0.756,0.899 and 0.737.No patients experienced complications such as hematoma.Conclusions FNAB with 10 ml vacuum pressure had the highest accuracy.

关 键 词：超声 细针抽吸活检 甲状腺结节 

分 类 号：R445.1[医药卫生—影像医学与核医学] R581[医药卫生—诊断学]