磁共振feature tracking初步评价终末期肾病患者心肌形变  

MR feature tracking in preliminarily assessment on myocardial deformation in patients with end-stage renal disease

作　　者：牟安娜[1] 李智勇[1] 张晨[1] 李梦颖[1] 宋清伟[1] 金凤强 刘爱连[1] 

机构地区：[1]大连医科大学附属第一医院放射科,辽宁大连116011

出　　处：《中国医学影像技术》2016年第6期881-884,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的采用心脏磁共振feature tracking(CMR-FT)技术初步分析终末期肾病患者左心室心肌形变各参数的变化情况。方法对10例正常志愿者和9例终末期肾病接受血液透析治疗的患者行1.5T心脏非对比增强、FIESTA序列电影成像,并采用feature tracking(FT)2D模型对左心室运动及整体心肌形变情况进行定量分析。结果终末期肾病患者左心室心肌质量[(132.70±44.44)g]大于正常志愿者[(80.00±11.29)g,P<0.05]。终末期肾病患者左心室心肌整体径向应变、环向应变、径向收缩期峰值运动速度、径向舒张期峰值运动速度均低于健康志愿者[(22.52±10.41)%vs(39.46±7.10)%,(-12.57±3.91)%vs(-19.80±2.11)%,(22.70±5.72)mm/s vs(34.77±3.81)mm/s,(-24.71±8.83)mm/s vs(-43.88±8.89)mm/s,P均<0.05)。而终末期肾病患者和正常志愿者的左心室射血分数、左心室舒张末期容积、左心室收缩末期容积差异无统计学意义(P均>0.05)。结论 CMR-FT技术能够定量评价终末期肾病患者左心室心肌运动及形变情况。Objective To preliminarily assess left ventricular myocardial deformation using cardiac magnetic resonance feature tracking（CMR-FT）in patients with end-stage renal disease（ESRD）.Methods Totally 10 healthy volunteers and9 patients with ESRD underwent cardiac non-contrast cine imaging with FIESTA sequence on 1.5T MRI scan.Left ventricular myocardial deformation and motion were quantitatively evaluated by 2D-mode.Results The left ventricular mass in patients with ESRD（[132.70±44.44]g）was higher than that in healthy group（[80.00±11.29]g,P〈0.05）.Global peak radial strain,peak circumferential strain,radial systolic velocity,radial diastolic velocity of left ventricular myocardium in patients with ESRD were lower than them in healthy volunteers（[22.52±10.41]% vs[39.46±7.10]%,[-12.57±3.91]% vs[-19.80±2.11]%,[22.70±5.72]mm/s vs[34.77±3.81]mm/s,[-24.71±8.83]mm/s vs[-43.88±8.89]mm/s,all P〈0.05）.But,the other left ventricular function parameters,such as left ventricular ejection fraction（LVEF）,left ventricular end-diastolic volume（LVEDV）and left ventricular end-systolic volume（LVESV）had no difference between patients with ESRD and healthy volunteers（all P〉0.05）.Conclusion CMR-FT could quantitatively evaluate left ventricular myocardial motion and deformation in patients with ESRD.

关 键 词：磁共振成像 特征追踪 终末期肾病 形变 

分 类 号：R692.5[医药卫生—泌尿科学] R445.2[医药卫生—外科学]