亚洲骨质疏松自我评价工具对北京房山地区部分绝经后妇女早期筛检效果评价  

Early evaluation of screening ability of OSTA for postmenopausal women in Beijing Fangshan

作　　者：杜娜[1] 刘婷[1] 王秋萍[1] 

机构地区：[1]北京市房山区良乡医院,102401

出　　处：《首都食品与医药》2016年第12期41-43,共3页Capital Food Medicine

摘　　要：目的：观察亚洲骨质疏松自我评价工具（OSTA）对北京房山地区部分绝经后妇女骨质疏松（OP）的早期筛查效果。方法本研究共招募412名绝经后健康女性受试者，用双能X线骨密度仪（dual energy X-ray absorptiometry, DXA）测量腰椎L2～L4、左股骨近端（股骨颈、Ward 三角、大转子）的BMD值和T值，根据公式计算亚洲骨质疏松自我评价工具（OSTA）得分，按OSTA＞-1、OSTA≤-1分为低、中高危险2级，构建ROC曲线，计算灵敏度、特异度、ROC曲线下面积。结果 OSTA诊断骨质疏松症的敏感度73.5%，特异度59.2%。ROC曲线的AUC及其95%CI为0.748（0.691，0.804）。结论本研究发现， OSTA指数筛查绝经后妇女骨质疏松的敏感性一般，不建议单独作为早期骨质疏松筛查工具。Objective To evaluate the early screening effect of OSTA for osteoporosis in l women of Fangshan area.Methods A total of 412 postmenopausal women were measured by dual energy x-ray absorptiometry（DXA）in this study, measuring the Bone Mineral Density（BMD） and T-scores of lumbar vertebrae L2 to 4、left proximal femur Neck （femoral neck,Ward’s triangle,greater rochanter）.Osteoporosis Self-assessment tool for Asians index was calculated. All persons were classified into low and middle risk group by OSTA index OSTA〉-1, OSTA≤-1, ROC curve construction,sensitivity calculation,specificity calculation, area under ROC curve.Results OSTA diagnosis the sensitivity, specificity of osteoporosis were 73.5%, 59.2%. The AUC of ROC curve and 95%CI were 0.748（0.691,0.804）.Conclusion This study found that OSTA index is not an ideal tool for screening early stage osteoporosis in postmenopausal women.

关 键 词：骨质疏松症 骨密度(BMD) 亚洲骨质疏松自我评价工具(OSTA) 双能X线吸收测量法(DXA) 

分 类 号：R580[医药卫生—内分泌]