机构地区:[1]深圳市慢性病防治中心结核病防治科,518020 [2]深圳市慢性病防治中心办公室,518020
出 处:《中国防痨杂志》2016年第6期486-492,共7页Chinese Journal of Antituberculosis
基 金:“十二五”国家科技重大专项(2012ZX10004903);深圳市科技计划项目(JCYJ20140416103315869)
摘 要:目的探讨深圳市学生肺结核发病的主要影响因素,为完善学校结核病防控策略提供科学依据。方法采用1:2配对病例对照研究方法,选取2014年9月至2015年12月在深圳市各区结核病防治机构确诊的130例学生肺结核患者(病例组)及260名健康者(对照组)进行问卷调查,应用SPSS17.0软件进行条件多因素logistic回归分析。结果单因素分析显示:体质量指数(BMI)〈18.5(Wald x2=6.074,P=0.014)、母亲文化程度(高中、中职或大专:Wald x2=6.261,P=0.012;本科及以上:Wald x2=8.797,P=0.003)、睡眠时间(≥8h/d)(Wald x2=7.510,P=0.006)、经常熬夜(Waldx2=4.932,P=0.026)、锻炼时间〈0.5h/d(除体育课之外;Wald x2=7.586,P=0.006)、学习生活有压力(“偶有压力”,Wald x2=5.023,P=0.025;“经常有压力”,Wald x2=6.066,P=0.014)、上学形式(住校;Wald x2=4.904,P=0.027)、居住情况(≥2人/间;Wald x2=6.861,P=0.009)、课外经常参与室内活动(Wald x2=5.059,P=0.024)、存在校外结核病接触史(Wald x2=8.088,P=0.004)、未接受结核病防治知识教育(Wald x2=15.504,P=0.000)等是肺结核发病的影响因素。多因素分析结果显示:BMI〈18.5(β=0.582,Wald x2=5.235,OR=1.790,95%CI=1.087~2.948,P=0.022)、锻炼时间〈0.5h/d(除体育课之外;β=1.302,Wald x2=7.054,OR=3.676,95%CI=1.407~9.608,P=0.008)、居住≥2人/间(β=1.384,Wald x2=6.766,OR=3.991,95%CI=1.407-11.326,P=0.009)、上学形式(住校;p=0.824,Wald x2=10.630,OR=2.279,95%CI=1.389~3.740,P=0.001)、校外结核病接触史(β=0.741,Wald x2=6.914,OR=2.098,95%CI=1.208~3.645,P=0.009)和未接受结核病防治知识教育(β=0.967,Wald x2=14.891,OR=2.629,95%C1=1.609-4.295,P=0.000�Objective To explore the influencing factors of the pulmonary tuberculosis (TB) among students in Shenzhen, and to provide evidence for school TB prevention, Methods A 1 : 2 matched case-control study using questionnaire investigation was implemented in 130 TB students (patient group) diagnosed in Tuberculosis Prevention and Control Institutions in Shenzhen during September 2014 and December 2015, and 260 healthy students (control group). SPSS 17.0 was used for conditional multi-factor logistic regression analysis. Results Uni- variate conditional logistic regression analysis showed that some factors, including body mass index (BMI) 〈18.5 (Wald x2 = 6. 074, P=0. 014), maternal educational level (senior high school or secondary vocational school or jun- ior college: Wald x2 = 6. 261, P= 0. 012 ; undergraduate or above: Wald x2 = 8. 797, P = 0. 003), sleeping more than 8 hours per day (Wald Z2 =7. 510,P=0. 006), always stay up late (Wald ;x2 =4. 932,P=0. 026), exercise in addition to physical education less than half an hour per day on average (Wald x2 =7. 586, P=0. 006), pressure in life or study (feel stressful occasionally: Wald x2 = 5. 023, P= 0. 025 ; feel stressful constantly: Wald x2 = 6. 066, P=0. 014), in residence (Wald x2 =4. 904, P=0. 027), more than two persons living in a room (Wald X2= 6. 861, P=0. 009), always participate in the indoor activities (Wald X2 = 5. 059, P = 0. 024), exposure to TB outside the school (Wald x2= 8. 088, P= 0. 004) and no education for TB common sense before (Wald X2= 15. 504, P=0. 000), were associated with the TB of students. Multi-univariate conditional logistic regression analy- sis showed that BMI 18.5 (p=0. 582,Wald 2 =5. 236, OR=1. 790, 95%CI=1. 087-2. 948,P=0. 022) ,exer- cise in addition to physical education less than half an hour a day on average (x2= 1. 302, Wald x2 = 7. 054, OR = 3. 676,95%CI=1. 407--9. 608,P=0. 008), more than two person living in a room (/9=1. 384, Wald x2 =6. 76
关 键 词:结核 肺 危险因素 病例对照研究 回归分析 学生
分 类 号:R195.1[医药卫生—卫生统计学] X2[医药卫生—卫生事业管理]
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...