合成生物学概念解析、风险评价与管理  

Concept Analysis, Risk Assessment and Regulation of Synthetic Biology

作　　者：关正君[1,2] 裴蕾 魏伟[2] 马克平[2] 

机构地区：[1]运城学院生命科学系,运城044000 [2]中国科学院植物研究所/环境与植被变化国家重点实验室,北京100093 [3]Biofaction KG,奥地利维也纳1030

出　　处：《农业生物技术学报》2016年第7期937-945,共9页Journal of Agricultural Biotechnology

基　　金：运城学院博士科研启动项目(No.YQ-2014022);欧盟地平线2020项目(EU Horizon 2020,grant no.634942)

摘　　要：合成生物学作为现代生命科学技术发展最前沿的技术之一,在医学、制药、化工、农业、生物能源、生物材料、生物环境治理等领域,具有巨大的潜在应用价值,但由此也带来一系列的潜在风险和安全问题,引起社会各界的极大关注和高度重视。本文将从合成生物学的概念发展、合成生物学相关研究内容涉及的安全评价现状,以及世界各国针对合成生物学研究现状提出的监管方案和安全应对举措等方面综合分析合成生物学这一新型的研究领域对人类和环境的潜在影响。As one of most cutting-edge technologies of life science, synthetic biology has great potential to develop into valuable applications in several research fields such as medical science, pharmaceuticals,chemical industry, agricultural science, biofuels, bio-materials and bioremediation. However, it may also bring up potential risks, which attracts great attentions from not only research community but also the society at large. This paper will first review how the concept of synthetic biology has developed; the potential risks and biosafety concerns raised from its research and applications; and the existing regulatory frameworks from the key players of synthetic biology around the world. Based on this knowledge, we will conduct a comprehensive analysis on the potential implications of synthetic biology on the human and environment.

关 键 词：合成生物学 概念 潜在风险 生物安全 监管 

分 类 号：Q81[生物学—生物工程]