中西医结合治疗高脂血症疗效观察  

Therapeutic Effect of Integrated Traditional Chinese and Western Medicine Treating Hyperlipidemia

作　　者：陈申杰[1] 徐晓明[1] 李波[1] 

机构地区：[1]浙江省中医院心血管科,浙江杭州310003

出　　处：《中华中医药学刊》2016年第6期1387-1389,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省中医药科技计划项目(2015374628)

摘　　要：目的:探讨中西医结合治疗高脂血症患者疗效观察。方法:收治的高脂血症患者130例据随机数字表法随机分为中西医组65例与西医组65例。西医组给予辛伐他汀治疗,中西医组在辛伐他汀基础上结合自拟中药汤剂。两组疗程均为4周。比较两组治疗总有效率,治疗前后血脂指标、血液流变学指标、凝血功能指标水平变化及治疗期间不良反应情况。结果:中西医组总有效率(93.85%)高于西医组(75.38%)(P<0.05);中西医组血脂指标TC、TG、LDL-C治疗后低于西医组(P<0.05),HDL-C高于西医组(P<0.05);中西医组血液流变学指标血浆黏度、全血高切黏度、全血低切黏度、红细胞压积治疗后低于西医组(P<0.05);中西医组凝血功能指标TT、PT、APTT治疗后低于西医组(P<0.05);两组均未见严重用药不良反应。结论:中西医结合治疗高脂血症患者疗效明显,且可降低患者血脂、改善患者血液流变学及凝血功能,具有重要价值。Objective： To investigate the effect of combined Chinese and Western medicine on treating hyperlipidemia.Methods： A total of 130 patients with hyperlipidemia were randomly divided into Chinese and Western medicine group 65 cases and Western medicine group 65 cases. The western medicine group was given simvastatin treatment and traditional Chinese and Western medicine group combined TCM Decoction on the basis of simvastatin group. Two groups＇ treatment was 4 weeks. Compare the total effective rate of the two groups,the changes of blood lipid index,blood rheology index and blood coagulation function index before and after treatment and adverse reactions during treatment. Results： The total effective rate of Chinese and Western medicine group（ 93. 85%） was higher than that of Western medicine group（ 75. 38%）（ P〈0. 05）. LDL-C,TG and TC in the treatment of Chinese and Western medicine group were lower than those in western medicine group（ P〈0. 05） and HDL-C was higher than that in Western medicine group（ P〈0. 05）.Traditional Chinese medicine and Western medicine group＇s indexes of hemorheology and plasma viscosity,blood viscosity at high shear rate,low blood shear viscosity and hematocrit were lower than those of the Western medicine group（ P〈0. 05）. TT,PT and APTT of coagulation function in Chinese and Western medicine group were lower than the western medicine group＇s after treatment（ P〈0. 05）. After treatment,Chinese and Western medicine group＇s TT,PT and APTT were lower than the Western medicine group＇s（ P〈0. 05）. No serious drug adverse reactions were observed in the two groups. Conclusion： Combined Chinese and Western medicine treatment of hyperlipidemia has obvious curative effect and can reduce the blood lipids and improve the blood rheology and coagulation function,with important value.

关 键 词：中西医 高脂血症 疗效 

分 类 号：R543[医药卫生—心血管疾病]