基于仲景柴胡方证理论运用柴胡加龙骨牡蛎汤治疗失眠的临床研究  

Therapeutic Effect of Bupleurum Falcatum plus Dragon Bone and Oyster Shell Decoction on Insomnia Based on Theory of Bupleurum Falcatum Decoction Originated from ZHANG Zhongjing

作　　者：王斌 张谈 裘磊 林吉品[2] 

机构地区：[1]慈溪市中医医院,浙江慈溪315300 [2]慈溪市人民医院,浙江慈溪315300

出　　处：《中华中医药学刊》2016年第6期1430-1433,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省中医药科学研究基金项目(2014ZB106)

摘　　要：目的:研究以仲景柴胡方证理论为基础,运用柴胡加龙骨牡蛎汤治疗失眠的临床效果。方法:肝郁化火型失眠患者80例,随机分为对照组和治疗组各40例。对照组每晚睡前口服谷维素片2片,每天1次;治疗组给予柴胡加龙骨牡蛎汤每日1剂水煎服,早晚分两次服用。两组均以连续服药4周为1疗程。比较治疗前后两组疗效,主要症状积分,睡眠质量量表积分和停药6个月后的复发率。结果:治疗后,对照组总有效率为72.5%,治疗组总有效率为87.5%,与对照组相比,疗效显著提高(P<0.05);治疗2周,4周和停药2周后,对照组匹兹堡睡眠指数比治疗前无明显变化,治疗组兹堡睡眠指数均分别低于治疗前和对照组相应时段,差异有显著性(P<0.05)。对照组失眠,头痛,烦躁易怒,胸闷胁痛等主要症状积分与治疗前相比,无显著差异(P>0.05),治疗组上述各主要症状积分与治疗前相比均显著降低(P<0.05),治疗结束后随访6个月,对照组的复发率为85%,治疗组的复发率为5%,治疗组复发率显著低于对照组(P<0.05)。结论:柴胡加龙骨牡蛎汤治疗失眠疗效可靠。Objective： To observe the therapeutic effect of Bupleurum Falcatum plus Dragon Bone and Oyster Shell Decoction（ CJLM） on insomnia. Methods： Eighty insomnia patients were divided into control group and treatment group randomly. Control group received Oryzanol Tablet 200 mg once a day in the evening while treatment group received CJLM twice a day at the same time. Both groups were treated for 4 weeks as a course. Before and after treatment,the total effective rate,main symptom scores and recovery rate were compared between two groups. Results： The total effective rate in control group was 72. 5%,which was much lower than 87. 5% in treatment group（ P〈0. 05）. The main symptom scores in treatment group were significantly decreased after treatment（ P〈0. 05） while there was no obvious change in control group. Compared with the control group,the sleeping quality score in treatment group was significantly decreased（ P〈0. 05）. The recovery rate in treatment group was obviously lower than that of control group（ P〈0. 05）. Conclusion：CJLM was effective in treating insomnia.

关 键 词：仲景柴胡方证理论 柴胡加龙骨牡蛎汤 失眠 

分 类 号：R256.23[医药卫生—中医内科学]