278例胰腺癌证素特征分析  

Syndrome Character Study of 278 Pancreas Cancer Cases

作　　者：王彤[1] 吴承玉[1] 杨涛[1] 

机构地区：[1]南京中医药大学基础医学院,南京210023

出　　处：《中国实验方剂学杂志》2016年第12期220-223,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金青年科学基金项目(81503499);江苏省高校自然科学研究项目(15KJB360006)

摘　　要：目的:探析胰腺癌病位、病性证素特征,规范胰腺癌的病位、病性特征表现。方法:设计前瞻性观察方案,按统一的诊断、纳入、排除标准,选取278例胰腺癌临床病例,应用SPSS 18.0软件对常见症状进行聚类分析,归纳提示胰腺癌病位和病性相关系数较高的症状、体征和舌脉表现;将一般症状、舌象、脉象分别进行主成分分析,归纳总结胰腺癌临床常见证型。结果:278例胰腺癌临床病例显示胰腺癌主要病位为脾、肝、胃、胆、肾,分别占100%,58.6%,50.7%,27.3%,20.5%;主要病性为血瘀、气滞、气虚、湿、痰、热,分别占100%,74.1%,66.2%,59.7%,38.8%,34.5%。常见证型包括肝胆湿热证、肝郁脾虚证、痰瘀互结证、肝肾阴虚证、脾虚水停证。结论:278例胰腺癌病例提示基础病位在脾,基础病性为痰、瘀,相兼病位胃、肝、胆、肾,相兼病性气滞、湿、热、水停。胰腺癌基本治则是健脾助运、化痰逐瘀,根据相兼病位、病性的不同,选用行气、通腑、利胆、祛湿、清热等法。Objective： To study disease location character and disease feature character of pancreas cancer in order to standardize the characteristic features of pancreas cancer. Method： Prospective observation,clustering and principal component analysis on common disease syndromes of pancreas cancer was done by SPSS18. 0 software. Result： Pancreas cancer cases showed that the main disease location of pancreas cancer were spleen,liver, stomach, gallbladder and kidney, taking 100%,58. 6%,50. 7%,27. 3%,20. 5%; main disease features were blood stasis, Qi stasis, Qi deficiency, dampness, phlegm and hot, taking 100%,74. 1%,66. 2%,59. 7%,38. 8%,34. 5%,respectively. In clinic,commonly seen syndrome types include syndrome of damp-heat in liver and gallbladder, syndrome of stagnation of liver qi and spleen deficiency,syndrome of intermin-gled phlegm and blood stasis,syndrome of yin deficiency of liver and kidney,syndrome of spleen deficiency and water retention. Conclusion： Pancreas cancer cases indicates that the main disease location of pancreas cancer were spleen,liver,stomach,gallbladder and kidney and main disease features were blood stasis,Qi stasis,Qi deficiency,dampness,phlegm and hot.

关 键 词：胰腺癌 病位特征 病性特征 病例聚类 主成分分析 

分 类 号：R241[医药卫生—中医诊断学] R287[医药卫生—中医临床基础]