降脂宁颗粒的HPLC指纹图谱  

HPLC Fingerprints of Jiangzhining Granules

作　　者：刘敏[1] 贾海红[1] 高飞萌 律涛[2] 樊淑彦[1] 

机构地区：[1]河北医科大学药学院药物分析教研室,河北石家庄050017 [2]河北医科大学药学院实验中心,河北石家庄050017

出　　处：《中国医药工业杂志》2016年第6期767-770,共4页Chinese Journal of Pharmaceuticals

摘　　要：建立了降脂宁颗粒的HPLC指纹图谱。采用Diamonsil C18色谱柱,以甲醇(A)∶0.1%磷酸(B)为流动相,梯度洗脱,检测波长286 nm。检测了10批降脂宁颗粒,以2,3,5,4'-四羟基二苯乙烯-2-O-?-D-葡萄糖苷为参照峰,标定了25个共有峰,并进行了归属。10批样品除1批相似度仅0.731外,其余9批相似度均大于0.9。The HPLC fingerprints of Jiangzhining granules were established. A Diamonsil C18 column was used, with the mobile phase of methanol ： 0.1% phosphoric acid by gradient elution, at the detection wavelength of 286 nm. Ten batches of Jiangzhining granules were analyzed. There were 25 common peaks marked with the peak of 2,3,5,4＇-tetrahydroxyl dibenzoethylene-2-O-β-D-glucoside as the reference and their assignment was completed. The similarities of these samples were all over 0.9 except one batch （0.731）.

关 键 词：降脂宁颗粒 高效液相色谱 指纹图谱 

分 类 号：O657.72[理学—分析化学] TQ460.72[理学—化学]