3784例Ⅰ类切口手术围术期预防性用药调查及切口感染情况分析  被引量:7

Investigation and Analysis on Prophylactic Use of Antibiotics and Incision Infections of Type ⅠIncision in 3784 Cases During Perioperative Period

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作  者:黄玉玲 肖志斌 杨辉 刘佩坚 马海燕 陈健民 

机构地区:[1]广州市番禺区中心医院药学部,广东广州511400 [2]广州市番禺区中心医院医教科,广东广州511400

出  处:《中国医院用药评价与分析》2016年第5期667-669,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘  要:目的:了解专项整治活动后Ⅰ类切口手术围术期预防性用药及切口感染的情况,为合理用药提供参考。方法:抽取2014年广州市番禺区中心医院(以下简称"我院")所有Ⅰ类切口手术病例3 784例,分析围术期预防性用药的合理性、切口感染率及切口感染的药物相关因素。结果:3 784例Ⅰ类切口手术患者中,736例预防性使用抗菌药物,抗菌药物预防性使用率为19.45%。736例预防性使用抗菌药物患者中,选药合理724例(占98.37%),给药时间合理674例(占91.58%),用药疗程<24 h 407例(占55.30%),用药疗程<48 h 650例(占88.32%),联合用药3例(占0.41%),不合理用药69例(占9.38%);重点监控的腹股沟疝修补术围术期预防性用药率为6.38%(19/298),甲状腺(含甲状旁腺)疾病手术围术期预防性用药率为0.85%(6/707),乳腺疾病手术及经血管途径介入诊断手术围术期预防性用药率均为0%。3 784例Ⅰ类切口手术患者中,8例患者发生术后切口感染,切口感染率为0.21%。结论:为期3年的抗菌药物专项整治活动大大提高了我院Ⅰ类切口手术围术期预防性用药的合理性,规范Ⅰ类切口手术围术期预防性用药并不会增加术后切口感染率,而围术期不规范的预防性用药却可能增加术后切口感染的风险。OBJECTIVE: To investigate the prophylactic use of antibiotics and incision infections of type Ⅰincision in 3 784 cases during perioperative period,so as to provide reference for the rational drug use. METHODS:3 784 cases with type Ⅰ incision were extracted from Guangzhou Panyu District Central Hospital( hereinafter referred to as "our hospital ") in 2014,the related factors as rationality,rate of incision infection and drugs for incision infection were analyzed during perioperative period. RESULTS: Of the 3 784 cases,736 cases had prophylactic use of antibiotics,the rate of prophylactic use of antibacterial was 19. 45%. Among the 736 cases,724 cases were rational drug use( 98. 37%),674 cases were proper delivery time( 91. 58%),407 cases were in treatment course less than24 h( 55. 30%),650 cases were in treatment course less than 48 h( 88. 32%),3 cases were in drug combination( 0. 41%),and 69 cases were irrational drug use( 9. 38%). The rates of prophylactic use of antibiotics in the mainly monitored inguinal hernia repair surgery,thyroid surgery,breast surgery and percutaneous coronary intervention surgery were respectively 6. 38%( 19 /298),0. 85%( 6 /707) and 0%. Of the 3 784 cases,there were 8 cases of incision infection,the rate was 0. 21%. CONCLUSIONS: The rectification activity of antibiotics greatly contributes to promoting the rational use of antibiotics in our hospital during the three years. Normative prophylactic antibiotics of type Ⅰ incision would not increase the rate of surgical incision infection. However,un-normative prophylactic antibiotics of type Ⅰ incision may increase the risk of surgical incision infection.

关 键 词:Ⅰ类切口手术 预防用抗菌药物 切口感染 

分 类 号:R978.1[医药卫生—药品]

 

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