SOD-like Activities of SOD and Cu(Ⅱ)Complexes inLiposomes  

SOD和Cu（Ⅱ）络合物脂质体的SOD样活性

作　　者：刘艳[1] 李连涛[1] 孙静[1] 鲁纯素[1] 

机构地区：[1]北京医科大学药学院

出　　处：《Journal of Chinese Pharmaceutical Sciences》1995年第4期177-180,共4页中国药学（英文版）

摘　　要：The SOD-like activities of SOD, four Cu(Ⅱ)Complexes, SOD-and Cu(Ⅱ)com-plex-liposomes were determined respectively by using cytochrome C method. The results showed that all of these systems had SOD-like activities to some extent of which the Cu(His)_2-liposome displayed the highest activity and the Cu(Ⅱ)complexes and liposomes had some positive cooperative action.用Ｃｙｔ．ｃ－ＨＸ－ＸＯ法分别测定了ＳＯＤ和４种Ｃｕ（Ⅱ）络合物及脂质体的ＳＯＤ样活性。结果表明：所有体系均有某种程度的ＳＯＤ样活性，其中组氨酸酮脂质体的ＳＯＤ样活性最高，Ｃｕ（Ⅱ）络合物与脂质体具有一些协同作用。

关 键 词：Superoxide radical Cu(Ⅱ)Complexes LiposomeIntroductionThis project was supported by National Natural Science Foundation of China 

分 类 号：R944.9[医药卫生—药剂学] R977.5[医药卫生—药学]