淋巴管肌瘤病实验室检测指标的变化  

Changes of indices for lymphangioleiomyomatosis

作　　者：赵旭宏[1] 霍萌[1] 杨淼[1] 侯军林[1] 

机构地区：[1]首都医科大学附属北京世纪坛医院医学检验科,北京100038

出　　处：《检验医学》2016年第6期509-512,共4页Laboratory Medicine

摘　　要：目的分析淋巴管肌瘤病（LAM）的实验室指标,以期能为其诊疗起到提示作用.方法对38例LAM患者的实验室检测指标{血常规[白细胞（WBC）、血红蛋白（Hb）、血小板（PLT）] 、肝功能[丙氨酸氨基转移酶（ALT）、天门冬氨酸氨基转氨酶（AST）、总蛋白（TP）、白蛋白（Alb）]、肾功能[肌酐（Cr）]、血清葡萄糖（Glu）、甘油三酯（TG）、肿瘤标志物[糖类抗原（CA）125]、总补体活性、血气指标[pH值、氧分压（PO2）、二氧化碳分压（PCO2）] }进行回顾性分析. 结果LAM患者血常规及肝、肾功能无明显变化.血气结果提示存在不同程度的酸中毒.90.91%的患者CA125水平明显升高,升高幅度超出参考区间上限3-30倍不等.75.84%的患者血清总补体活性升高,但升高幅度不大,均在参考区间上限的1倍以内.结论LAM患者的CA125及血气结果有明显改变.Objective To analyze the indices for lymphangioleiomyomatosis(LAM),and provide a reference for its diagnosis and treatment. Methods A retrospective analysis was performed for 38 LAM patients. Indices of routine blood tests [white blood cell(WBC),hemoglobin(Hb) and platelet(PLT)],liver function [alanine aminotransferase(ALT),aspartate aminotransferase(AST),total protein(TP) and albumin(Alb)], kidney function [creatinine(Cr)],serum glucose(Glu),triglyceride(TG),tumor marker[carbohydrate antigen(CA)125],total complement and blood gas [p H,partial pressure of oxygen(PO_2) and partial pressure of carbon dioxide(PCO_2)] were analyzed. Results In LAM patients,the results of routine blood tests,liver function and kidney function had no significant changes. The results of blood gas showed that LAM patients existed different degrees of acidosis. CA125 of 90.9% LAM patients increased and exceeded the upper limit of reference interval for 3 times to 30 times. Serum total complement of 75.84% LAM patients increased slightly and within 1 time of the upper limit of reference interval. Conclusions CA125 and blood gas results of LAM patients have significant changes.

关 键 词：淋巴管肌瘤病 糖类抗原125 血气 总补体 

分 类 号：R446.1[医药卫生—诊断学]