Isolation and Identification of Ecliptasaponin A andEcliptasaponin B from Eclipta alba(L.)Hassk  

旱莲草化学成分旱莲甙A和旱莲甙B的分离和鉴定

作　　者：张梅[1] 陈雅妍[1] 

机构地区：[1]北京医科大学药学院

出　　处：《Journal of Chinese Pharmaceutical Sciences》1996年第4期177-181,共5页中国药学（英文版）

摘　　要：Two new triterpenoid glucosides ecliptasaponin A(3)and ecliptasaponin B(4)were isolated together with echinocystic acid(1)and oleanolic acid(2)from Eclipta alba(L.) Hassk.Their structures were deduced as 3β,16a-dihydroxy olean-12-ene-28-oic acid-3β-O-β-D-glu-copyranoside(3)and 3β-O-[β-D-glucopyranosyl(1-4)]-β-D-glucopyranosyl-16a-hydroxy olean-12-ene-28-oic acid 28-O-β-D-glucopyranoside(4),based on spectral analysis and chemical evidences as well as results ofhydrolysis.自旱莲草全草（Ｅｃｌｉｐｔａａｌｂａ（Ｌ．）Ｈａｓｓｋ）中分得４个三萜化合物，经理化常数测定和光谱（ＩＲ，ＭＳ，ＵＶ，￣１ＨＮＭＲ，１３ＣＮＭＲ和１３Ｃ－１ＨＣＯＳＹ）解析，２个已知的三萜化合物分别为刺囊酸（ｅｃｈｉｎｏｃｙｓｔｉｃａｃｉｄ，１）和齐墩果酸（ｏｌｅａｎｏｌｉｃａｃｉｄ，２），另２个为新化合物，分别命名为旱莲甙Ａ（ｅｃｌｉｐｔａｓａｐｏｎｉｎＡ，３）和旱莲甙Ｂ（ｅｃｌｉｐｔａｓａｐｏｎｉｎＢ，４）。

关 键 词：Eclipta alba(L.)Hassk Triterpenoid glucoside Ecliptasaponin A Ecliptasaponin B 

分 类 号：R284.1[医药卫生—中药学]