Antioxidant Constituents from G. inflata Bat Root  

胀果甘草抗氧化活性成分的研究

作　　者：邹坤[1] 赵玉英[1] 傅乃武[1] 乔梁[1] 张如意[1] 

机构地区：[1]北京医科大学药学院,中国医学科学院肿瘤研究所

出　　处：《Journal of Chinese Pharmaceutical Sciences》1996年第4期182-185,共4页中国药学（英文版）

摘　　要：Continuing the previous report(1),seventeen compounds were isolated from the roots and rhizoma of Glycyrrhiza inflata Bat. On the basis of spectroscopic methods five of them were identified as sucrose(1),4’,5,7-trihydroxy-8-prenyl-flavonc(2),liquiritigenin(3),formononetin(4),and glabrone(5)(1),(4)and(5)were obtained from this plant for the first time. Their antioxidant activities were observed in three oxidizing systems in vitro.(2),(3)and(5)showed remarkable activities in scavenging(5 exhibited good activity in inhibiting hemolysis induced by H_2O_2(3)and(5)displayed higher inhibitory action on (HpD + hv)-induced hemolysis than som typical antioxidants.继前文￣（１）工作，又从胀果甘草根茎中获得了十七个化合物。其中五个鉴定为１：蔗糖，２：４’，５，７－三羟基－８－异戊烯－黄铜，３：甘草素，４：芒柄花素，５：光甘草酮。化合物１，４，５为首次从该植物中获得。在三个体外氧化体系中观察了它们的抗氧化活性。２，３，５显示出显著的清除的活性，５对Ｈ＿２Ｏ＿２诱导的溶血具有良好的抑制作用，３。

关 键 词：Glycyrrhiza inflata Flavonoids Glabrone ANTIOXIDANT 

分 类 号：R285.5[医药卫生—中药学]