血府逐瘀汤对脑外伤患者血浆NSE、CRP的影响及临床疗效观察  

Clinical Efficacy Study of Xuefuzhuyu Soup for Plasma NSE, CRP in Brain Injury Patients

作　　者：秦德芳[1] 张泽舜[1] 马丁[1] 李丽 

机构地区：[1]广东省中医院珠海医院,广东珠海519000 [2]珠海市卫生学校,广东珠海519000

出　　处：《深圳中西医结合杂志》2016年第9期40-41,共2页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:探究血府逐瘀汤治疗脑外伤患者的临床疗效及其对患者血浆神经元特异性烯醇化酶(NSE)、C反应蛋白(CRP)的影响。方法:以2013年1月—2015年10月广东省中医院珠海医院收治的112例脑外伤患者为研究对象,依治疗方法将患者分为两组。对照组54例,患者行西医基础治疗。观察组58例,患者在对照组治疗基础上加用血府逐瘀汤汤剂治疗,1剂/d。对比两组患者治疗后的神经功能情况、日常生活能力情况及血浆中NSE和CRP的变化情况。结果:治疗后,观察组患者美国立卫生研究院卒中量表(NIHSS)评分(8.5±2.4),Barthel指数评分(81.3±12.2),两项指标与对照组比较,差异具有统计学意义(P<0.05);治疗后,观察组患者NSE平均下降(10.62±5.04)μg/L,CRP平均下降(9.75±4.13)mg/L,与对照组比较,差异具有统计学意义(P<0.05)。结论:血府逐瘀汤可有效降低患者NSE、CRP水平,改善患者神经功能,提升患者日常生活能力。Objective To explore the clinical efficacy of blood Treated patients with brain injury and its effect on plasma NSE（neuron-specific enolase）, CRP（C-reactive protein） in. Methods 112 cases of traumatic brain injury patients in our hospital were studied from January 2013-October 2015, according to the method of treatment will be selected were divided into two groups. Among them, the control group, 54 patients underwent western medicine, including reducing the intracranial pressure, reduced edema, antibiotics, nutrition cells. 58 cases in the experimental group, patients in the control group therapy based on the use of blood Xuefuzhuyu soup Decoction, one dose a day. Compare two groups of neurological patients after treatment, daily living conditions and changes in plasma NSE and CRP. Results After treatment, the experimental group NIHSS score（8.5 ± 2.4）, Barthel Index score（81.3 ± 12.2）, two indicators significantly better than the control group, the difference was statistically significant（P〈 0.05）;After treatment, the experimental group NSE fell by an average（10.62 ± 5.04） μg / L, CRP mean decrease（9.75 ± 4.13） mg / L, with the experimental comparison group difference was statistically significant（P 〈0.05）. Conclusion Xuefu wind and soup can effectively reduce the patient NSE, CRP levels and improve neurological function, improve patients＇ daily living skills and should be introduced in the clinical treatment of traumatic brain injury patients.

关 键 词：血府逐瘀汤 脑外伤 神经元特异性烯醇化酶 

分 类 号：R651.15[医药卫生—外科学]