原发性遗尿症儿童功能性膀胱容量与遗尿程度的相关性  

Correlation between functional bladder capacity and severity of nocturnal enuresis among children with primary enuresis

作　　者：潘晓芬[1] 刘玉玲[1] 付四毛[1] 雷辛衍[1] 李性希[1] 林国模[1] 

机构地区：[1]南方医科大学附属中山市博爱医院儿科,广东中山528403

出　　处：《中国妇幼健康研究》2016年第5期571-573,共3页Chinese Journal of Woman and Child Health Research

基　　金：广东省医学科研基金(A2015609);中山市科技计划资助项目(2015B1167)

摘　　要：目的探讨原发性遗尿症儿童功能性膀胱容量减少的年龄分布,以及功能性膀胱容量（FBC）与遗尿程度的相关性。方法选取南方医科大学附属中山市博爱医院2010-2015年期间收治的原发性遗尿症儿童为研究对象,整理患者临床资料,问卷调查其遗尿程度（平均遗尿次数）,并通过超声自动容量测定出膀胱容量,分析两者相关性。结果共纳入研究对象693例,其中男422例（占60.9%）,女271例（占39.1%）。年龄7.48±2.15岁,最小5岁,最大16岁。有遗尿家族史者211例,占30.4%。遗尿严重程度（平均次数）为〈1次/d有318例（占45.9%）,1次/d有260例（占37.5%）,〉1次/d有115例（占16.6%）。功能性膀胱容量减少发生达533例,占76.9%。各年龄组FBC减少的发生率差异无统计学意义（χ2=3.340,P=0.342）。在5~7岁和〉9~11岁儿童中,FBC减少组的重度遗尿（〉1次/d）的比例均明显高于FBC正常组（χ2值分别为12.185、9.477,均P〈0.05）;在〉7~9和〉11~16岁儿童中,FBC减少组的重度遗尿的比例较低,差异均无统计学意义（均P〉0.05）。按照遗尿严重程度分组,各组间FBC与预期膀胱容量（EBC）比值中位数分别为44.05%,39.38%,36.67%,经秩和检验有统计学意义,χ2=9.858,P=0.007。结论原发性遗尿症患者多数存在着FBC减少,与遗尿程度具有相关性,重度遗尿症FBC与正常值的比值相对较低。Objective To study the age distribution of children with primary enuresis whose functional bladder capacity （FBC） decrease and the correlation between FBC and severity of nocturnal enuresis. Methods Primary noeturia children admitted in Affiliated Zhongshan Bohi Hospital of Southern Medical University during 2010-2015 were enrolled as research objects. Clinical data of patients were collected. Questionnaire was used to survey severity of enuresis （average frequency of enuresis）, bladder capacity was determined automatically by ultrasonic bladder capacity, and the correlation between them was analyzed. Results Totally 693 eases were enrolled, including 422 males （60.9%） and 271 females （39.1%）. The average age was 7.48 ±2.15 years old （ranging 5-16）. There were 211 cases with family history of enuresis, accounting for 30.4%. There were 318 cases （45.9%） with enuresis frequency （average frequency） 〈 1/d, 260 cases （37.5%） with frequency of 1/d and 115 cases （16.6%） with frequency 〉 1/d. FBC decrease occurred in 533 cases, accounting for 76.9%. The difference in incidence of reduced FBC was not significant among groups （X2 = 3. 340, P = 0. 342）. Among children aged 5-7 and 9-11, the proportion of severe enuresis （ 〉 1/d） in reduced FBC group was significantly higher than that in FBC normal group （X2 value was 12. 185 and 9. 477, respectively, both P 〈0.05）. Among children aged 8 -9 and 11 -16, the proportion was low in reduced FBC group, and the difference was not significant （ both P 〉 0. 05 ）. Grouped by the severity, the median of FBC over EBC was 44.05% , 39.38% and 36.67% , respectively （X2 = 9. 858, P = 0. 007 ）. Conclusion Most of children suffering primary enuresis have reduced FBC, which is associated with the severity of enuresis. The ratio of FBC of severe enuresis cases over normal value is relatively low.

关 键 词：原发性遗尿症 功能性膀胱容量 遗尿程度 相关性 

分 类 号：R726.9[医药卫生—儿科]