陕西省育龄期女性多囊卵巢综合征流行病学特点分析  

Epidemiological characteristics of PCOS of reproductive age women in Shaanxi Province

作　　者：高婷婷[1] 李博[1] 陈书强[1] 董杰[1] 王晓红[1] 

机构地区：[1]第四军医大学唐都医院妇产科生殖医学中心,陕西西安710038

出　　处：《中国妇幼健康研究》2016年第5期584-586,共3页Chinese Journal of Woman and Child Health Research

基　　金："十二五"国家科技支撑计划资助项目(项目号:2012BAI32B0)

摘　　要：目的探讨陕西省多囊卵巢综合征(PCOS)女性的流行病学特点。方法回顾性分析2014年2至9月间第四军医大学唐都医院妇产科生殖医学中心调查的69例PCOS组患者与276对照组女性的遗传因素、诱发因素及临床特点,并对结果进行分析。结果与对照组相比,PCOS组母亲及姐妹月经稀发率、父亲及兄弟早秃率、吸烟率、饮酒率、经常吃高热量食品率、盆腔炎患病率差异均无统计学意义(均P>0.05);PCOS组腰臀比均值、子宫内膜厚度、舒张压均值、初潮年龄与对照组比较差异也均无统计学意义(均P>0.05);PCOS组的身体质量指数(BMI)均值、收缩压均值、不孕率均显著高于对照组,差异均有统计学意义(BMI:t=2.45;收缩压:t=2.80;不孕率:χ2=10.93,均P<0.05);PCOS组月经稀发及闭经率、卵巢多囊样改变率、多毛痤疮率、高雄血症率均显著高于对照组,差异均有统计学意义(月经稀发及闭经率:χ2=120.95;卵巢多囊样改变率:χ2=195.07;多毛痤疮率:χ2=6.78;高雄血症率χ2=64.75,均P<0.05)。结论在陕西省调查人群中,PCOS患病率稍低于国外统计数据、但仍有明显的BMI、月经稀发及闭经、卵巢多囊样改变、多毛痤疮、高雄血症的特点;同时伴有收缩压、不孕率的显著增高;因此,对PCOS女性的定期检查预防远期并发症有着重要意义。Objective To explore the epidemiological characteristics of women with polycystic ovary syndrome （ PCOS ） in Shaanxi Province. Methods Retrospectively analysis was conducted on genetic factors, inducing factors and clinical characteristics of 69 cases of PCOS in assisted reproduction center of Tangdu Hospital of Fourth Military Medical University and 276 controls during February to September 2014, and results were analyzed. Results The rates of mother and sisters＇ oligomenorrhea, father and brothers＇ premature balding, smoking, drinking, often eating high-calorie foods and prevalence of pelvic inflammatory disease were not remarkably difterent between two groups （ all P 〉 0.05 ）. The waist-to-hip ratio, thickness of endometrium, average systolic blood pressure and menarche age in PCOS group were also not significantly different from those in control group （ all P 〉 0.05 ）. Compared to the control group, mean BMI, average systolic blood pressure and infertility rate were significantly higher in PCOS group （ t value was 2.45 and 2.80, X2 = 10.93, all P 〈 0.05 ）, and the incidence of oligomenorrhea and amenorrhea, polycystic ovarian morphology, hairy and ache, high androgen hematic disease were also significantly higher （X2 value was 120. 95, 195. 07, 6.78 and 64. 75, respectively, all P 〈 0. 05 ）. Conclusion Prevalence of PCOS in Shaanxi Province is slightly lower than the foreign statistical data, but there are still obvious characteristics of BMI and prevalence of oligomenorrhea and amenorrhea, polycystic ovarian morphology, hairy and ache as well as high androgen disease. At the same time, systolic blood pressure and infertility rate increase significantly. Therefore, periodic inspeetion is of great importance to prevent long-term complications of PCOS women.

关 键 词：多囊卵巢综合征 流行病学 临床特点 肥胖 

分 类 号：R711.75[医药卫生—妇产科学]