肾移植术后1年以上稳定期患者生命质量问卷调查及其相关因素分析  

Quality of life and related factors in renal transplantation recipients of stable stage

作　　者：张强[1] 胡小鹏[1] 石慧[2] 刘航[1] 薛文瑞[1] 徐岳[1] 王伟[1] 张小东[1] 

机构地区：[1]首都医科大学附属北京朝阳医院泌尿外科,100020 [2]首都医科大学附属北京朝阳医院临床心理科,100020

出　　处：《中华全科医师杂志》2016年第6期468-471,共4页Chinese Journal of General Practitioners

基　　金：基金项目：国家自然科学基金（81270837）;北京市自然科学基金（7132107）;北京市医院管理局临床医学发展专项（ZYLX201408）;北京市卫生系统高层次卫生技术人才培养计划（2013-3-015）

摘　　要：对2015年2-4月在我院门诊随访的255例因慢性肾功能不全尿毒症期行肾移植治疗手术后1年以上的稳定期患者,采用健康调查简表（SF-36量表）评价生命质量.其中男性153例,女性102例;年龄21 ～81岁.SF-36量表评分分别是生理功能（80.8±2.0）分、生理职能（62.9±5.2）分、躯体疼痛（77.0±2.4）分、总体健康（53.7±2.9）分、情感职能（68.2±5.2）分,低于四川地方常模（t值分别为-9.9、-6.3、-4.5、-9.3和-3.1,均P＜0.05）;活力（69.4±2.0）分、社会功能（86.5±3.0）分、精神健康（70.8±2.1）分,与四川地方常模比较差异无统计学意义（均P ＞0.05）.肌酐水平（β=-0.2）、骨密度（β=0.2）、血红蛋白值（β=0.3）、BMI（β=-0.2）是肾移植受者生命质量的影响因素（均P＜0.05）.提示肾移植受者的生命质量仍低于健康人群,其影响因素是多方面的.The purpose of this article is to analyze the factors related to quality of life （QOL） in renal transplantation recipients of stable stage.The QOL of 255 renal transplantation recipients in stable stage,including 153 males and 102 females aged 21-81 years,was evaluated by 36-Item Short Form Health Survey （SF-36）.The related factors to QOL were analyzed with multivariate regression method.Results showed that the scores of 5 items in SF-36 of recipients after transplantation were low than those in general population in Sichuan province：physical function （80.8 ± 2.0）,role physical （62.9 ± 5.2）,bodily pain （77.0 ± 2.4）,general health （53.7 ± 2.9） and role emotional （68.2 ± 5.2） （t =-9.9,-6.3,-4.5,-9.3 and-3.1,all P 〈 0.05）;while there were no differences in scores of 3 items in SF-36 between recipients and general population in Sichuan province：vitality （69.4 ± 2.0）,social function （86.5 ± 3.0）and mental health （70.8 ± 2.1）.Multivariate regression revealed that serum creatinine level （β =-0.2）,bone mineral density（β =0.2）,hemoglobin （β =0.3）and BMI（β =-0.2） were associated with QOL （all P 〈 0.05）.The study indicates that QOL of renal transplantation recipients is still lower than that of general population and various factors affect QOL of renal transplantation recipients.

关 键 词：肾移植 生活质量 问卷调查 

分 类 号：R699.2[医药卫生—泌尿科学]