新疆阿克苏地区适龄儿童免疫抗体水平检测结果分析  

Analysis of immune antibody levels test results in preschool children in Aksu prefecture of Xinjiang

作　　者：王鲜芬[1] 董伟[1] 周红亮[1] 刘艳[1] 杜小燕[1] 周权[1] 

机构地区：[1]新疆阿克苏地区疾病预防控制中心,新疆843000

出　　处：《中国卫生检验杂志》2016年第11期1597-1599,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的通过检测了解阿克苏地区目标人群白喉、A群流脑及甲型、乙型肝炎抗体水平,为阿克苏地区开展免疫规划工作提供科学依据。方法按分层抽样法在全地区综合医院抽取3个适龄儿童组共1 095份血清,采用酶联免疫（ELISA）法分组检测白喉IgG、A群流脑IgG抗体、甲型肝炎IgG及乙型肝炎表面抗体。结果白喉IgG、乙肝抗体、A群流脑IgG和甲型肝炎IgG抗体总阳性率分别为56.48%、80.05%、92.67%和97.60%。不同性别白喉IgG抗体、乙型肝炎表面抗体、甲型肝炎IgG抗体阳性率差异均无统计学意义（χ^2值分别为0.535 7、2.108 0、0.460 8,P〉0.05）;不同性别A群流脑抗体水平阳性率差异有统计学意义（χ2=5.361 7,P〈0.05）。不同民族白喉IgG抗体、甲型肝炎IgG抗体阳性率差异均有统计学意义（χ^2值分别为30.936、15.187,P〈0.05）;乙型肝炎表面抗体、A群流脑抗体阳性率差异均无统计学意义（χ^2值分别为2.094 3、0.003,P〉0.05）。结论阿克苏地区地区目标人群甲型肝炎IgG抗体水平较高,白喉IgG抗体水平则较低,提示在今后的工作中,在做好基础免疫的同时,要重视强化免疫接种质量的管理。Objective By detecting the antibody levels of diphtheria,group A epidemic meningitis,hepatitis A and hepatitis B in the target population of Aksu prefecture,so as to provide scientific basis for carrying out immunization planning. Methods According to stratified sampling method,1 095 cases of serum were collected from the preschool children in grade three hospitals in the whole district,and immuneosorbent assay（ ELISA） method was used to detect IgG antibody of diphtheria,group A epidemic meningitis,hepatitis A and the surfance antibody of hepatitis B. Results The total positive rates of IgG antibody of diphtheria,hepatitis B,group A epidemic meningitis and hepatitis A were respectively 56. 48%,80. 05%,92. 67% and 97. 60%. The differences on positive rates of IgG antibody of diphtheria,hepatitis B surface,hepatitis A between different genders had no statistical significance（ χ^2= 0. 535 7,2. 108 0,0. 460 8,respectively,P〈0. 05）; while,there was statistical significance on the differences of IgG antibody positive rate between different genders（ χ~2= 5. 361 7,P〈0. 05）. The difference of IgG antibody positive rates of diphtheria,hepatitis A of different ethnic groups were statistically significant（ χ^2= 30. 93 6,15. 187,P〈0. 05）; the differences on positive rate of IgG antibody in hepatitis B surface and group A epidemic meningists were not statistically significant（ χ^2= 2. 094 3,0. 003,P〈0. 05）. Conclusion The IgG antibody levels of hepatitis A were higher and that of diphtheria were lower in target population in Aksu prefecture. The results suggest that on the basis of doing a good job in the basic immunization,we should pay attention to strengthen immunization quality management in the future work.

关 键 词：目标人群 白喉 甲型肝炎 乙型肝炎 A群流脑 抗体 

分 类 号：R186[医药卫生—流行病学]