桐乡市成人麻疹抗体水平调查分析  

Investigation and analysis of measles antibody levels in adults of Tongxiang

作　　者：严卓琳[1] 王春梅[1] 许皓[1] 郭敏建 

机构地区：[1]桐乡市疾病预防控制中心,浙江桐乡314500

出　　处：《中国卫生检验杂志》2016年第11期1648-1649,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的了解桐乡市20岁以上健康成人麻疹抗体水平,为制定成人麻疹防控策略提供科学数据。方法选择桐乡市20岁～49岁人群,按照自愿原则,采集血清,采用间接酶联免疫法定量检测麻疹Ig G抗体,对抗体阳转率、保护率、抗体浓度水平进行评价。结果共调查1 166人,麻疹抗体阳性率为83.45%、保护率为41.68%、几何平均滴度（GMC）为549.60 IU/L;抗体阳性率、保护率和GMC均随着年龄组上升而上升,差异均有统计学意义（P〈0.05）。结论桐乡市成人麻疹易感人群数量庞大,其中20岁～34岁人群麻疹抗体水平较低,不仅自己是高危人群,还导致新生儿体内无母传麻疹保护性抗体,建议在常规麻疹疫苗免费接种基础上,应鼓励育龄妇女接种麻疹疫苗。Objective To investigate the measles antibody levels of healthy adults aged more than 20 at Tongxiang,so as to provide scientific basis for the establishment of measles prevention and control strategy on adults. Methods Adults at Tongxiang among 20-49 years old were conducted for serum collection according to the principal of volunteerness. Indirect enzyme linked immunosorbent assay（ ELISA） was used to detect measles Ig G antibody,and the protective rate and antibody concentration were evaluated. Results A total of 1 166 participants were detected,with the positive rate,protection rate and geometric mean titers of measles antibody as 83. 45%,41. 68% and 549. 6 IU / L,respectively,which increased with ages,with the differences statistically significant（ P〈0. 05）. Conclusion There are large amounts of measles susceptible adults at Tongxiang,and the measles antibody among adults aged 20-34 are lower. Not only their own are high-risk group,but also lead to lack of maternal fetal transmission protective antibodies in the neonatal,it is recommended,on the basis of free vaccination of conventional measles vaccine,we should encourage women in childbearing age to vaccinate measles vaccine.

关 键 词：成人 麻疹 抗体水平 

分 类 号：R511.1[医药卫生—内科学]