结肠黑变病54例分析  

Analysis of melanosis coli in 54 cases

作　　者：韩静[1] 孙光斌 张宝芹[1] 王柏清[1] 李甜甜[1] 

机构地区：[1]天津市第五中心医院消化科,天津300450

出　　处：《中国现代医学杂志》2016年第11期102-104,共3页China Journal of Modern Medicine

摘　　要：目的 分析结肠黑变病（MC）的病因、诊断及预后。方法 选取该院2009年9月-2012年9月经电子结肠镜、病理学诊断的MC患者54例进行临床分析,并对其中的34例随访1年。结果 54例MC占同期结肠镜检查的0.13%（54/4120）,女性高于男性;年龄40~88岁,平均年龄70.2岁。病因以慢性便秘为主,占96.29%（52/54）,另有2例因其他疾病服用中草药〉6个月。诊断主要依靠电子结肠镜检查,对发现的结肠息肉取活检送病理学检查。对随访1年的34例患者复查电子结肠镜,其黏膜黑变程度无明显减轻,结肠息肉发生率无明显升高,未发现肿瘤新生物。结论 MC的病因明确,诊断主要依靠结肠镜检查,但短期干预治疗收效甚微,需长期随访观察。Objective To summarize etiology, diagnosis and prognosis of melanosis coli. Methods Fiftyfour cases of melanosis coli were treated in our hospital from Sep. 2009 to Sep. 2012 after electronic colonoscopy and pathological diagnosis. A retrospective clinical analysis was made for them. Of the 54 patients, 34 were followed up for one year. Results The 54 cases of melanosis coli accounted for 0.13% of those （54/4120） receiving colonoscopy in the three years and the female had a higher incidence. The average age was 70.21 （40-88） years. Chronic constipation was the cause of 52 cases （96.29%） while the other two had taken herbs for at least 6 months. Electronic colonoscopy was the main means of diagnosis, and biopsy and pathological examination were performed for colon polyps found in electronic colonoscopy. After one-year follow-up, 34 cases were re-examined, the extent of melanosis eoli was not relieved; the incidence of colon polyp was not obviously increased. Conclusions Etiology of melanosis coli is clear. Electronic eolonoscopy is the main means of diagnosis. Long-term follow-up is needed when short-term intervention is not efficient.

关 键 词：结肠黑变病 便秘 随访 

分 类 号：R754.62[医药卫生—皮肤病学与性病学]