呈色素改变的不典型家族性慢性良性天疱疮  

Atypical case of familial benign chronic pemphigus presented as hyperpigmentation

作　　者：陈菲[1] 周飞红[2] 

机构地区：[1]湖北中医药大学临床医学院,湖北武汉430065 [2]武汉市第一医院皮肤科,湖北武汉430000

出　　处：《临床皮肤科杂志》2016年第7期520-522,共3页Journal of Clinical Dermatology

摘　　要：报告1例呈色素改变的不典型家族性慢性良性天疱疮。患者女,42岁。双侧腋窝、窝出现网状色素沉着斑1年,皮损增多伴颜色加深,并双侧腹股沟出现同性质皮损半年余。组织病理示:表皮轻度增生,基底层色素增加,并可见棘层松解细胞,呈倒塌砖墙样外观,真皮浅层可见噬色素细胞浸润及血管周围淋巴细胞为主的浸润。诊断为家族性慢性良性天疱疮。A 42-year-old female presented with aggressive reticular pigmentation on her both axillae and popliteaI fossae for one year, and on bilateral inguinal regions for 6 months. Histopathological examination showed epidermal hyperplasia, hyper- pigmentation in the basal layer, acantholytic cells forming ＂dilapidated brick wall＂, and perivascular infiltration of lymphocytes and melanophages in the upper dermis. The diagnosis of familial benign chronic pemphigus was made.

关 键 词：家族性慢性良性天疱疮 不典型 色素改变 

分 类 号：R758.66[医药卫生—皮肤病学与性病学]