钛硅分子筛催化合成酮肟的工艺研究  

The synthesis of oxime catalyzed by titanium silicalite

作　　者：卢福军[1,2] 唐晓婵[2] 岳涛[2] 王伟文[1] 冯维春[2] 

机构地区：[1]青岛科技大学化工学院,山东青岛266042 [2]山东省化工研究院,山东济南250014

出　　处：《应用化工》2016年第6期1036-1039,1044,共5页Applied Chemical Industry

基　　金：山东省"泰山学者"建设工程基金项目(TS20130918);山东省自主创新及成果转化专项(2014ZZCX01501)

摘　　要：以钛硅分子筛为催化剂,过氧化氢为氧化剂,催化酮氨肟化合成酮肟,研究了不同的酮氨肟化反应的结果,并考察了各因素对酮催化氨肟化反应的影响。结果表明,n(酮)∶n(NH_3)∶n(H_2O_2)=1∶1.3∶2.5,加料方式为氨水和双氧水同时滴入,温度为65℃,催化剂加入量为4%,反应最佳溶剂为异丙醇,双氧水浓度对反应无明显影响,在最佳反应条件下,酮的转化率可以达到99%以上,肟的选择性高于99%。Ketoxime was synthesized by catalytic ammoxidation using titanium silicalite sieve as catalyst,hydrogen peroxide as oxidant.Studies different ketoximes on ammoximation reactions,many factors affecting the ammoxidation reaction are studied.Result showed that n（ketone）∶n（NH3）∶n（H2O2） is 1∶1.3∶2.5,ammonia and hydrogen peroxide dropping at the same time,suitable temperature is 65 ℃,catalyst concentration on ammoximation is 4%,the best solvets is isopropanol,concentration of hydrogen peroxide has no significant effects on the reaction.Under optimum conditions,the ketone conversion rate can exceed 99%,oxime selectivity higher than 99%.

关 键 词：钛硅分子筛 氨肟化 H2O2 异丙醇 选择性 

分 类 号：TQ224.7[化学工程—有机化工]