气虚血瘀证脑卒中患者心血管危险因子与NIHSS评分的关系研究  

Correlation Study of the Cardiovascular Risk Factors and NIHSS Score in Qi-Xu-Xue-Yu Stroke Patients

作　　者：汪欣[1] 吴旋[1] 陈云欢[1] 蔡梅玉[1] 程颖[1] 

机构地区：[1]福建中医药大学附属康复医院,福建福州350000

出　　处：《中国医学创新》2016年第17期110-113,共4页Medical Innovation of China

基　　金：2013年福建省卫生厅中医药科研项目(wzkf201308);2013年福建中医药大学临床类校管科研课题(XB2013048);2015年福建中医药大学重点学科专项校管课题(X2014076-学科)

摘　　要：目的:观察颈动脉IMT值、超敏C反应蛋白以及同型半胱氨酸在气虚血瘀脑卒中患者中的水平,评估三者与NIHSS评分的关系。方法:选取脑卒中患者139例,采用美国国立卫生研究院卒中量表(NIHSS)进行神经功能缺损程度评分,同时运用颈动脉彩超检测颈动IMT值,全自动生化分析仪检测血清同型半胱氨酸,免疫层析技术检测超敏C反应蛋白,观察结果。结果:气虚血瘀证患者与非气虚血瘀证患者NIHSS评分比较差异有统计学意义(P<0.05)。颈动脉IMT值、血清同型半胱氨酸以及超敏C反应蛋白在不同程度的NIHSS评分中比较差异有统计学意义(P<0.05)。重型神经功能损伤组中三者水平均呈明显上升。结论:检测气虚血瘀证脑卒中患者颈动脉IMT值、超敏C反应蛋白以及同型半胱氨酸等心血管危险因素,有利于从实验室和影像学的角度客观地判断脑卒中后神经功能的损伤程度,对脑卒中后神经功能的恢复有重要的临床意义。Objective：To observe the carotid IMT values, hypersensitive c-reactive protein and homocysteine levels in qi-xu-xue-yu stroke patients,and assess the relationship with NIHSS score. Method：A total of 139 cases of stroke patients were selected.The nerve function defect score was assessed by The national institutes of health stroke scale（NIHSS）.The carotid IMT value was detected by Carotid artery color ultrasound.The serum homocysteine was detected by automatic biochemical analyzer and the hypersensitive c-reactive protein was detected by Immune chromatography technology.Result：Compared with non-Qi-XuXue-Yu stroke patients,there were significant difference of NIHSS score in Qi-Xu-Xue-Yu stroke patients.And there were statistically significant differences of carotid IMT, hypersensitive c-reactive protein and homocysteine levels in different NIHSS score（P〈0.05）.In heavy group,three levels increased most significantly.Conclusion：Detecting the carotid IMT values, hypersensitive c-reactive protein and homocysteine levels in Qi-Xu-Xue-Yu stroke patients are in favour of objectively judging the damage degree of neural function after cerebral infarction from the angle of the laboratory and imageology,which has important clinical significance for the recovery of neural function after cerebral infarction.

关 键 词：气虚血瘀 脑卒中 颈动脉内中膜厚度 超敏C反应蛋白 同型半胱氨酸 

分 类 号：R277.7[医药卫生—中医学]