儿童朗格汉斯细胞组织细胞增生症侵及胸腺和甲状腺的CT影像表现  

CT imaging findings of thymus or thyroid gland involved in Langerhans cell histiocytosis of pediatric patients

作　　者：胡迪[1] 段晓岷[1] 曹琪 彭芸[1] 

机构地区：[1]首都医科大学附属北京儿童医院影像中心,100045 [2]新世纪儿童医院影像中心

出　　处：《中华放射学杂志》2016年第6期451-454,共4页Chinese Journal of Radiology

摘　　要：目的：探讨分析儿童朗格汉斯细胞组织细胞增生症（Langerhans cell histiocytosis，LCH）累及胸腺、甲状腺的CT影像表现。方法回顾分析我院2006年1月至2015年2月间经病理及临床确诊LCH累及胸腺和甲状腺患儿治疗前CT影像表现特点。其中累及胸腺者共38例，累及甲状腺者共8例。结果累及胸腺者CT平扫表现为9例单纯肿大，17例不同程度钙化，9例肿大伴不同程度钙化，1例胸腺内可见气腔影，1例肿大伴钙化及气腔，1例肿大伴钙化及低密度灶。累及甲状腺者CT平扫及增强检查表现为双侧甲状腺对称或不对称性肿大，密度不均匀减低，增强病变累及区强化不明显。结论 LCH累及胸腺CT表现以钙化常见，可不伴有胸腺肿大。LCH累及甲状腺CT表现以肿大、异常密度伴相邻组织肿胀为主。Objective To investigate the CT imaging findings of thymus and thyroid gland involved in Langerhans cell histiocytosis（LCH） of pediatric patients. Methods CT image findings in pediatric patients with LCH confirmed by pathology and clinical diagnosis from January 2006 to February 2015 were retrospectively analyzed. By radiography, 38 cases＇ thymus gland were involved and 8 cases＇ thyroids gland were involved. Results Plain CT scan for thymus gland involved patients revealed 9 cases were shown as hyperplasia, 17 cases were shown as calcification, 9 cases were shown as hyperplasia with calcification, 1 case was shown as cavity, 1 case was shown as hyperplasia with calcification and cavity and 1 case was shown as hyperplasia with calcification and low density. Enhanced CT scan for thyroid gland involved patients showed bilateral or unilateral enlargement of thyroid gland with heterogeneous low density and unobvious enhancement. Conclusions Finely calcifications were the most common CT findings on thymus gland involved in LCH and might without hyperplasia. CT imaging of thyroid LCH exhibited an enlarged or normal size and abnormal density in the thyroid gland with adjacent soft tissues involved.

关 键 词：儿童 组织细胞增多症 朗格尔汉斯细胞 体层摄影术 x线计算机 胸腺 甲状腺 

分 类 号：R725.9[医药卫生—儿科] R816.92[医药卫生—临床医学]