DSA不同参数组合对颅脑器官辐射剂量影响的模体研究  

Assessment of DSA dose effect with different combinations of parameters on brain organs： a phantom study

作　　者：孙士龙[1] 周桂娟[2] 李传东[1] 王玉丽[1] 刘瑞宏[1] 贾绍田[3] 杜国生[4] 

机构地区：[1]中日友好医院放射诊断科,北京100029 [2]北京中医药大学东直门医院放射科 [3]北京煤炭总医院放射科 [4]北京市疾病预防控制中心防护所

出　　处：《中华放射学杂志》2016年第6期455-458,共4页Chinese Journal of Radiology

摘　　要：目的：探讨DSA附加滤过和采集野的不同参数组合对颅脑器官辐射剂量影响。方法采用血管造影机，调整不同采集野（分别为48、42、31、22 cm）和附加滤过（分别为0.9 mmCu＋1.0 mmAl、0.4 mmCu＋1.0 mmAl、0.1 mmCu＋1.0 mmAl），将采集野及附加滤过分别组合，对装入剂量计的仿真模体行正侧位二维造影采集（2D-DSA）及三维造影采集（3D-DSA）。采集过程中记录累积剂量面积乘积（DAP）和入射参考点的空气比释动能（AK），并测量垂体、左晶体、右晶体的吸收剂量。采用t＇检验比较2D-DSA和3D-DSA采集时吸收剂量的差异，采用Pearson相关检验分析DAP、AK参数与不同部位吸收剂量的差异。结果2D-DSA条件下（n=12），左晶体、右晶体、脑垂体的吸收剂量分别为（2.77±0.68）、（6.23±3.54）、（8.65±2.62）mGy，3D-DSA条件下（n=12）上述部位的吸收剂量分别为（1.78±0.82）、（2.18±1.15）、（3.32±0.64）mGy，差异均有统计学意义（t＇值分别为3.20、3.76和6.85，P均〈0.01）。DAP [（8739±5731）mGy·cm2]与脑垂体、左晶体、右晶体的吸收剂量[分别为（5.988±3.299）、（2.258±0.872）、（4.207±3.303）mGy]均具有相关性（r值分别为0.766、0.684、0.727，P均〈0.01）。AK值为（31±23）mGy，和脑垂体吸收剂量具有相关性（r值为0.894，P〈0.01）。受检者眼晶体辐射剂量随着附加滤过增加、采集野减小而减小，垂体的辐射剂量随着附加滤过增加、采集野增加而减小。结论头颈部DSA时，晶体和垂体的辐射剂量随附加滤过和采集野的不同变化，具有一定规律性，且3D-DSA辐射剂量低于2D-DSA。Objective To investigate the lens and pituitary dose impacted by additional filtration and collection field in head and neck DSA examinations. Methods All images were acquired by a Philips ALLura Xper FD 20 DSA machine. The combination of the different collection fields （48 cm, 42 cm, 31 cm, 22 cm） and additional filtrations （0.9 mmCu＋1.0 mmAl, 0.4 mmCu＋1.0 mmAl, 0.1 mmCu＋1.0 mmAl） were adjusted when the anthropomorphic phantom filled with dosimeter was scanned in anterioposterior and lateral positions with 2D-DSA and 3D-DSA. The dose area product （DAP）, air kerma （AK） and the radiation dose values of bilateral lens and pituitary were measured and recorded. The 2D and 3D-DSA regional absorption dose on lens and pituitary were analyzed using t＇ test, the correlations between DAP and AK parameters and different regional absorption doses were evaluated by Pearson rank correlation coefficient. Results Absorption doses of left lens, right lens and pituitary with 2D-DSA （n=12） were as following：（2.77 ± 0.68）, （6.23 ± 3.54）, （8.65 ± 2.62） mGy, while the parameters with 3D-DSA （n=12） were （1.78 ± 0.82）, （2.18±1.15）, （3.32±0.64） mGy, respectively;the results revealed a significant difference （t＇=3.20, 3.76 and 6.85, P〈0.01）. DAP [（8 739±5 731） mGy·cm2] had a relationship with absorption dose of pituitary, left lens and right lens [（5.988 ± 3.299）,（ 2.258 ± 0.872）,（ 4.207 ± 3.303） mGy, r values were 0.766, 0.684, 0.727; P〈0.01]. AK values was （31 ± 23） mGy and it had a relationship with pituitary absorption dose （r value was 0.894, P〈0.01）. The lens dose was reduced when the additional filtration was increased and the collection field was decreased, the radiation dose of the pituitary was reduced when both the additional filtration and the collection field were increased. Conclusions In the head and neck DSA examinations, the radiation dose of the lens and the pituitary had different changes with the different addition

关 键 词：血管造影术 数字减影 辐射剂量 垂体 晶体 

分 类 号：R816.1[医药卫生—放射医学]