从“天人相应”探讨年节律对健康人皮肤屏障功能的影响  

Effects of Seasonal Variation on Skin Barrier Function of Healthy Adults Based on Theory of Correspondence Between Man and Nature

作　　者：杨广智[1] 麦丽霞[1] 张婷[1] 聂宝顺 冯焕婷[1] 林佩玲[1] 刘倩霞 

机构地区：[1]南方医科大学附属小榄医院,广东中山528415

出　　处：《辽宁中医杂志》2016年第6期1214-1216,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：广东省中医药管理局科研究项目(20152090)

摘　　要：目的:从"天人相应"的角度出发,探讨年节律对健康人皮肤屏障功能的影响。方法:选取健康志愿者50例,男女各25例。检测其在生理状态下春分、夏至、秋分、冬至四个节气的皮肤经皮水分丢失(Trans Epidermal Water Loss,TEWL)、角质层含水量、油脂量、p H值等指标的变化,并进行统计分析。结果:1TEWL值:冬至最大,夏至最小,二者比较差异具有统计学意义(t=17.83,P<0.05)。2角质层含水量:面颊部春分最大,冬至最小,二者比较差异具有统计学意义(t=4.89,P<0.05)。颧部夏至最大,冬至最小,二者比较差异具有统计学意义(t=3.97,P<0.05)。3油脂量:夏至最多,秋分最少,二者比较差异具有统计学意义(t=5.25,P<0.05)。4p H值:冬至最大,夏至最小,二者比较差异具有统计学意义(t=4.69,P<0.05)。结论:结果提示皮肤屏障功能随季节变化而变化,夏季较好,冬季减弱。Objective： To explore the effects of seasonal variation on skin barrier function of healthy adults based on the theory of correspondence between man and nature. Methods： Fifty healthy volunteers were chosen,25 men and 25 women. The changes in physiological state of skin transepidermal water loss,stratum corneum hydration,sebum content and p H value were checked in the four solar terms of vernal equinox,summer solstice,autumnal equinox and winter solstice. The data obtained was statistically analyzed. Results： 1TEWL value： maximum in winter solstice,minimum in summer solstice. There was significant difference between the two groups（ t = 17. 83,P 〈 0. 05）. 2Stratum corneum hydration on the cheek： maximum in vernal equinox and minimum in winter solstice. There was significant difference between the two groups（ t = 4. 89,P 〈 0. 05）. On the malar,maximum in summer solstice and minimum in winter solstice. There was significant difference between the two groups（ t = 3. 97,P 〈 0. 05）. 3Sebum content： maximum in summer solstice,minimum in autumn equinox. There was significant difference between the two groups（ t =5. 25,P 〈 0. 05）. 4p H value： maximum in winter solstice,minimum in summer solstice. There was significant difference between the two groups（ t = 4. 69,P 〈 0. 05）. Conclusion： The results suggest that the skin barrier function changes with the seasons,better in the summer and weakened in the winter.

关 键 词：天人相应 时间医学 皮肤屏障功能 经皮水分丢失 角质层含水量 油脂量 PH值 

分 类 号：R2-03[医药卫生—中医学]