心理护理干预减轻心绞痛患者焦虑情绪的机制研究  

The mechanism of lessening effects induced by psychological nursing intervention on angina patients＇ anxiety

作　　者：闫红卫[1] 庞丽[2] 薛惠平[3] 邢希梅[4] 李红[5] 

机构地区：[1]山东省滨州市中心医院甲状腺乳腺外科,251700 [2]山东省滨州市中心医院肾内科,251700 [3]山东省滨州市中心医院急诊科,251700 [4]山东省滨州市中心医院神经内科,251700 [5]山东省滨州市中心医院骨科,251700

出　　处：《国际免疫学杂志》2016年第3期234-236,共3页International Journal of Immunology

摘　　要：目的探讨心理干预在心绞痛患者外科手术中对患者焦虑情绪的影响和可能的作用机制。方法选取85正常人群为对照组，将281例不稳定性心绞痛患者随机分为心绞痛组（138人）和心理护理干预组（143人）。对照组和心绞痛组接受常规临床护理，心理护理干预组接受访谈为主，音乐多媒体为辅的干预模式。放射免疫法测定血浆促肾上腺皮质激素（ACTH）、血管紧张素II（Ang）、血管紧张素转换酶（ACE）浓度水平。酶联免疫吸附试验（ELISA）检测血清中白细胞介素（IL）-6和IL-10的表达水平。结果和对照组相比，心绞痛组和心理护理干预组患者AngII、ACE、IL-6和IL-10水平呈不同程度升高，ACTH无显著变化；和心绞痛组相比，心理护理干预组降低了患者AngII、ACE和1L-6的表达水平。结论心理护理干预通过降低AngII、ACE和IL-6的表达水平来减轻心绞痛患者的焦虑情绪。Objective To investigate the mechanism of lessening effects induced by psychological nursing intervention on angina patients＇ anxiety. Methods 85 normal people were selected as control. 281 an- gina patients were divided into angina group and psychological nursing intervention group, each group has 138 and 143 patients. Control groups were treated with traditional clinical nursing. Psychological nursing intervention group were treated with interview primarily and assistance with multimedia. Radioimmunoassay was used to de- tect the concentration level of adrenocorticotropic hormone （ACTH）,angiotensin （AngIand AnglI） and angio- tensin converting enzyme （ACE） in plasma. Enzyme linked immunosorbant assay （ELISA） was used to detect the level of interleukin （IL）-6 and 10. Results Compared with control, the level of AngII, ACE, IL-6 and IL-10 showed increased in angina group and psychological nursing intervention group, while ACTH has no significant change. Compared with angina group, the level of AngII, ACE and IL-6 in psychological nursing intervention group showed decreased. Conclusion Psychological nursing intervention could alleviate angina patients＇ anxi- ety through decreasing the level of AnglI, ACE and IL-6.

关 键 词：心理护理干预 心绞痛 焦虑 

分 类 号：R473.5[医药卫生—护理学]