槐耳颗粒联合125^I放射性粒子植入术治疗中晚期肝癌的疗效分析  

Clinical analisis of Huaier granule combined with CT-gulded Iodine-125 （125I） particles implantation for advanced hepatoeellular carcinoma

作　　者：米彩锋[1] 余守雅 

机构地区：[1]河南省平顶山市第一人民医院消化内科,467000

出　　处：《中国实用医刊》2016年第11期75-77,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨槐耳颗粒联合125^I放射性粒子植入术治疗中晚期肝癌的疗效。方法选取116例原发性肝癌患者，将其随机分为A组52例和B组64例，A组单纯应用125^I放射性粒子植入术治疗，B组应用槐耳颗粒联合125^I放射性粒子植入术治疗。结果近期有效率：A组：42．3％，B组：73．4％，差异有统计学意义（P〈0．01）；甲胎蛋白降低率：A组：32．7％，B组：57．8％，差异有统计学意义（P〈0．05）；6个月生存率：A组59．6％，B组79．7％，差异有统计学意义（P〈0．05）。12个月生存率：A组21．2％，B组40．6％，差异有统计学意义（P〈0．05）。结论槐耳颗粒联合”’I放射性粒子植入术治疗中晚期肝癌，可提高有效率、甲胎蛋白降低率、6个月及12个月生存率。Objective To study the clinical effect of Huaier granule combined with CT-guided Io- dine-125（125^I） particles implantation on advanced hepatocellular carcinoma. Methods One hundred and sixteen patients who were diagnosed of advanced hepatocellular carcinoma were divided into two groups. The 52 patients as group A were treated by single CT-guided 125^I particles implantation. And the other 64 patients as group B were treated by Huaier granule combined with CT-guided 125^I particles implantation. The effective rate, AFP reduction rate, 6 months survival rate and 12 months survival rate were evaluated. Results The effective rate of group A and group B were 42. 3% was 73.5%, respectively, the difference were significant（P 〈0. 01）. The AFP reduction rate of group A and group B was 32. 7% and 57. 8%, the difference was significant（P 〈0. 05）. The 6 months survival rate of group A and group B was 59. 6% and 79. 7%, and that of group B was significantly higher than that of group A （P 〈0. 05）. The 12 months survival rate of group A and group B was 21.2% and 40. 6%, and that of group B was significantly higher than that of group A （P 〈0. 05）. Conclusions Huaier Granule combined with CT-guided 125^I particles implantation for advanced hepatocellular carcinoma may improve the effective rate, AFP reduction rate, 6 months survival rate and 12 months survival rate.

关 键 词：槐耳颗粒 125^I放射性粒子植入术 中晚期肝癌 

分 类 号：R735.7[医药卫生—肿瘤]