地塞米松与甲泼尼龙治疗突发性耳聋的临床疗效对比  

Compared the Clinical Efficacy of Dexamethasone and Methylprednisolone Treatment of Sudden Deafness

作　　者：陈晓华[1] 秦兆冰[1] 

机构地区：[1]郑州大学第一附属医院耳科,河南郑州450000

出　　处：《中国继续医学教育》2016年第15期170-171,共2页China Continuing Medical Education

摘　　要：目的对比分析甲泼尼龙与地塞米松治疗突发性耳聋的临床疗效。方法选取本院2013年9月-2015年11月收治的96例突发性耳聋患者作为本次实验的研究对象,根据用药种类的差异,将其分为对照组（n=48）及研究组（n=48）,对照组患者应用地塞米松鼓室灌注治疗,研究组患者则给予甲泼尼龙进行耳后皮下注射治疗,对比分析两组患者的临床效果和不良反应。结果研究组患者的治疗总有效率为89.58%,对照组患者的治疗总有效率为85.42%,组间数据差异无统计学意义（P〉0.05）;两组患者的不良反应对比差异无统计学意义（P〉0.05）。结论甲泼尼龙耳后皮下注射和地塞米松鼓室灌注治疗突发性耳聋的疗效显著,均能有效改善患者的临床症状,有助于恢复听力。Objective Comparison of the clinical efficacy of methylprednisolone and dexamethasone treatment of sudden deafness.Methods 96 cases of sudden deafness patients choosen from our hospital from September 2013 to November 2015 were treated as subjects of this experiment,based on differences in the type of medication,which was divided into the control group（n=48） and the study group（n=48）,patients in the control group tympanic dexamethasone infusion therapy,the study group patients were treated with methylprednisolone subcutaneously behind the ear,comparative analyzed of the clinical effects of two groups of patients,and adverse reactions.Results The study group of patients with total effective rate was 89.58%,the control group of patients with total effective rate was 85.42%,there was no significant difference between the two groups of data（P〉0.05）,adverse reaction compared two groups of patients（P〈0.05）.Conclusion After subcutaneous injection of methylprednisolone and dexamethasone ear tympanic infusion therapeutic effect of sudden deafness is significant,it can effectively improve the clinical symptoms of the patient,help to restore hearing.

关 键 词：地塞米松 甲泼尼龙 临床疗效 突发性耳聋 

分 类 号：R764[医药卫生—耳鼻咽喉科]